Formaldehyde dismutase

In enzymology, a formaldehyde dismutase (EC 1.2.99.4) is an enzyme that catalyzes the chemical reaction

2 formaldehyde formate + methanol
formaldehyde dismutase
Identifiers
EC no.1.2.99.4
CAS no.85204-94-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

Hence, this enzyme has one substrate, formaldehyde, and two products, formate and methanol.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with other acceptors. The systematic name of this enzyme class is formaldehyde:formaldehyde oxidoreductase. Other names in common use include aldehyde dismutase, and cannizzanase.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2DPH.

References

    • Kato N, Shirakawa K, Kobayashi H, Sakazawa C (1983). "The dismutation of aldehydes by a bacterial enzyme". Agric. Biol. Chem. 47: 39–46. doi:10.1271/bbb1961.47.39.


    This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.