Frailty index

The frailty index (FI) can be used to measure the health status of older individuals; it serves as a proxy measure of aging and vulnerability to poor outcomes.

Frailty index
An elderly couple out for a walk.
PurposeMeasure health status in elderly

FI was developed by Dr. Kenneth Rockwood and Dr. Arnold Mitnitski at Dalhousie University in Canada.

FI is defined as the proportion of deficits present in an individual out of the total number of age-related health variables considered. A frailty index can be created in most secondary data sources related to health by utilizing health deficits that are routinely collected in health assessments. These deficits include diseases, signs and symptoms, laboratory abnormalities, cognitive impairments, and disabilities in activities of daily living.[1]

Frailty Index (FI) = (number of health deficits present) ÷ (number of health deficits measured)

For example, a person with 20 of 40 deficits collected has an FI score of 20/40 = 0.5; whilst for someone with 10 deficits, the FI score is 10/40 = 0.25. The FI takes advantage of the high redundancy in the human organism. This is why it is replicable across different databases even when different items and different numbers of items are used. The standard procedure for creating a frailty index are found in an open-access publication.[2]

There are several frailty indices, including a clinical deficits frailty index (FI-CD) and a biomarker-based frailty index (FI-B).[3]

See also

References
  1. Peña, Fernando G.; Theou, Olga; Wallace, Lindsay; Brothers, Thomas D.; Gill, Thomas M.; Gahbauer, Evelyne A.; Kirkland, Susan; Mitnitski, Arnold; Rockwood, Kenneth (February 24, 2014). "Comparison of alternate scoring of variables on the performance of the frailty index". BMC Geriatrics (Research article). 14 (1): 25. doi:10.1186/1471-2318-14-25. PMC 3938909. PMID 24559204.
  2. Searle, Samuel D; Mitnitski, Arnold; Gahbauer, Evelyne A; Gill, Thomas M; Rockwood, Kenneth (September 30, 2008). "A standard procedure for creating a frailty index". BMC Geriatrics (Research article). 8 (1): 24. doi:10.1186/1471-2318-8-24. PMC 2573877. PMID 18826625.
  3. Mitnitski, Arnold; Collerton, Joanna; Martin-Ruiz, Carmen; Jagger, Carol; von Zglinicki, Thomas; Rockwood, Kenneth; Kirkwood, Thomas B. L. (July 13, 2015). "Age-related frailty and its association with biological markers of ageing". BMC Medicine (Research article). 13 (1): 161. doi:10.1186/s12916-015-0400-x. PMC 4499935. PMID 26166298.


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