Frank Fenner

Frank John Fenner AC CMG MBE FRS FAA (21 December 1914 – 22 November 2010) was an Australian scientist with a distinguished career in the field of virology. His two greatest achievements are cited as overseeing the eradication of smallpox,[2] and the attempted control of Australia's rabbit plague through the introduction of Myxoma virus.[3]

Frank Fenner

AC, CMG, MBE, FRS, FAA
Born
Frank Johannes Fenner

21 December 1914
Ballarat
Died22 November 2010(2010-11-22) (aged 95)[1]
Canberra
NationalityAustralian
Other namesFrank John Fenner (after 1938)
EducationUniversity of Adelaide
OccupationVirology
EmployerAustralian National University
Known forEradication of smallpox
Control of Australia's rabbit plague
SpouseEllen Margaret Bobbie Roberts
Parent(s)Albert Charles Fenner and Emma Louise "Peggy" Hirt

The Australian Academy of Science awards annually the prestigious Fenner Medal for distinguished research in biology by a scientist under 40 years of age.[4][5]

Early life and education

Frank Johannes Fenner was born in Ballarat in 1914. The family moved to Adelaide, South Australia in November 1916. He attended Rose Park Primary School and Thebarton Technical School. He attended the University of Adelaide, where he earned degrees in medicine and surgery in 1938. That year, uneasy about Hitler's rise, he legally changed his middle name to John.[6]

Career

In May 1937, Fenner was a member of an Adelaide University anthropological expedition to Nepabunna Mission in the northern Flinders Ranges in South Australia led by J.B. Cleland, which also included Charles P. Mountford as ethnologist and photographer, as well as botanist Thomas Harvey Johnston, and others.[7]

From 1940 to 1946 he was a Captain and Major in the Australian Army Medical Corps with service in Australia, Palestine, Egypt, New Guinea, and Borneo,[6] as medical officer in field ambulance and Casualty Clearing Station, pathologist to general hospital, and malariologist. For his work in combating malaria in Papua New Guinea he was made a Member of the Order of the British Empire in 1945.[8][9]

Following his war-time service he was recruited by Frank Macfarlane Burnet to work at the Walter and Eliza Hall Institute of Medical Research in Melbourne. Initially they worked on smallpox in mice, for which he coined the term "mousepox", and later on the genetics of poxvirus.

In 1949, he received a fellowship to study at the Rockefeller Institute for Medical Research in New York City, he worked on mycobacterium Bairnsdale bacillus, which causes Buruli ulcer, the third most important mycobacterial disease worldwide after tuberculosis and leprosy. Here he worked with and was influenced by René Dubos, who is one of the claimed originators of the phrase "Think Globally, Act Locally".

In Canberra, 1949–2010

Returning to Australia in 1949, he was appointed professor of microbiology at the new John Curtin School of Medical Research at the Australian National University, Canberra. Here he began studying viruses again, in particular the myxoma virus.

Throughout the 1940s and 1950s Australia had severe rabbit plagues. Fenner's work on the myxoma virus showed that initially it killed rabbits in 9 to 11 days and was 99.5% lethal. Under heavy selection pressure, the few rabbits that survived developed resistance, which meant that the pest was never completely eradicated, but their numbers were reduced. Prior to the release of the virus as a biological control for the rabbits, Fenner, Frank Macfarlane Burnet, and Ian Clunies Ross famously injected themselves with myxoma virus, to prove it was not dangerous for humans.

From 1967 to 1973 Fenner was Director of the John Curtin School of Medical Research. In 1977, he was named the chairman of the Global Commission for the Certification of Smallpox Eradication, the same year the last known case of naturally transmitted smallpox occurred in Somalia. Fenner announced the eradication of smallpox to the World Health Assembly on 8 May 1980.[6] This success story is regarded as the greatest achievement of the World Health Organization. Before its eradication, smallpox was one of the world's most virulent viruses, responsible for millions of deaths, and leaving many of the victims who survived with disfiguring scars for life.

Fenner had an abiding interest in the environment, and was the foundation Director of the Centre for Resources and Environmental Studies at the ANU (1973), where he worked until his retirement in 1979, and which became part of the Fenner School of Environment and Society in 2007.[10] He was a keen supporter of Australia having an ecologically, socially sustainable population. He was emeritus professor at the John Curtin School of Medical Research.

In June 2010, he predicted in an interview with The Australian the extinction of the human race within a century, primarily as the result of human overpopulation, environmental degradation and climate change.[6][11][12]

He died in Canberra on the morning of 22 November 2010 after a brief illness, and days after the birth of his first great-grandchild.[13]

Personal life

In 1944 Fenner met Bobbie Roberts. Ellen Margaret 'Bobbie' Roberts was a trained midwife and nurse. During World War II she worked on malaria with the Australian Army Nursing Service and through her work met Fenner.[14] Shortly after they met they married in a Catholic ceremony (despite Fenner being an atheist).[15] While keen to have children, the couple were infertile and with Bobbie having a hysterectomy in 1949 they decided to adopt. They subsequently adopted two children. Marilyn Aldus Fenner was born on 27 June 1950. Her biological parents were unknown. Victoria Fenner (born 1 March 1943) was adopted later at the request of her father (Fenner's younger brother Tom) after the death in a fire of Victoria's mother (Beverley Slaney).[16]

On 30 March 1958, Victoria Fenner shot and killed herself, with the assistance of another child, Catherine Webb. The coronial inquiry heard she had been passing through a period of extreme mental and spiritual disturbance and the coroner declared her death a suicide.[17] Fenner himself was unable to fathom a motive, other than she was upset from reading Neville Shute's book, On the Beach.[18]

Bobbie Fenner was diagnosed with cancer in 1989 and eventually died in 1994. Marilyn Fenner and her family then moved into the family home and looked after her father until his death.[19]

Publications
  • Frank Fenner and Francis Ratcliffe, Myxmatosis. Cambridge University Press, 1965. ISBN 0521049911
  • Fenner, Frank; Wittek, Riccardo; Dumbell, Keith R. (1988). The Orthopoxviruses. Elsevier. ISBN 978-0-323-15022-4.

Honours

Of the many honours Fenner received throughout his career, there are the following:

References
  1. Henderson, Donald A. (2011). "Frank Fenner (1914–2010) A guiding light of the campaign to eradicate smallpox". Nature. 469 (7328): 35. doi:10.1038/469035a. PMID 21209651.
  2. Frank F. Fenner, Donald A. Henderson, Isao Arita, Zdeněk Ježek, Ivan D. Ladnyi Smallpox and its Eradication World Health Organization Geneva, 1988
  3. Boyden, S.; Blanden, R.; Mims, C. (2013). "Frank John Fenner FAA. 21 December 1914 -- 22 November 2010". Biographical Memoirs of Fellows of the Royal Society. 59: 125–144. doi:10.1098/rsbm.2013.0009. hdl:1885/65529. S2CID 71415413.
  4. "Australian Academy of Science – Fenner medal". Archived from the original on 13 April 2014. Retrieved 13 April 2014.
  5. "UWA scientist wins Academy Award".
  6. Grimes, William (25 November 2010). "Frank Fenner Dies at 95; Tracked End of Smallpox". The New York Times.
  7. "Nepabunna, 1937–39". SA Memory. State Library of South Australia. 28 October 2009. Retrieved 13 November 2020.
  8. It's an Honour: MBE
  9. Citation record of MBE
  10. Fenner School of Environment and Society website
  11. Jones, Cheryl (15 June 2010). "Fenner sees no hope for humans". The Australian.
  12. Edwards, Lin (23 June 2010). "Humans will be extinct in 100 years says eminent scientist". Phys.org. Retrieved 2 July 2020.
  13. "Scientist Fenner dies aged 95". Australian Broadcasting Corporation. 22 November 2010.
  14. Encyclopaedia of Australian Science
  15. Chapter 3, Nature, Nurture and Chance: the lives of Frank and Charles Fenner
  16. Chapter 5, Nature, Nurture and Chance: the lives of Frank and Charles Fenner
  17. Suicide Finding in Death of Girl 15 in Canberra, Sydney Morning Herald, 20 June 1958, p3
  18. Chapter 5, Nature, Nurture and Chance: the lives of Frank and Charles Fenner
  19. Chapter 11, Nature, Nurture and Chance: the lives of Frank and Charles Fenner
  20. It's an Honour: CMG
  21. "Macfarlane Burnet Medal and Lecture". Australian Academy of Science. Retrieved 22 February 2017.
  22. It's an Honour: AC
  23. "World Cultural Council / Winners – Science – Frank Fenner". Archived from the original on 29 July 2013. Retrieved 14 August 2013.
  24. "Jon Stanhope appalled by ACT federal seat renamed from Fraser to Fenner". 24 November 2015.
  25. "Voters call out AEC on Fraser electorate renaming". 19 October 2015.
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