Fruit bromelain

Fruit bromelain (EC 3.4.22.33, juice bromelain, ananase, Bromelase (a trademark), bromelin, extranase, pinase, pineapple enzyme, traumanase, fruit bromelain FA2) is an enzyme.[1][2][3][4] This enzyme catalyses the following chemical reaction

Hydrolysis of proteins with broad specificity for peptide bonds. Bz-Phe-Val-Arg-NHMec is a good synthetic substrate
Fruit bromelain
Identifiers
EC no.3.4.22.33
CAS no.9001-00-7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

This enzyme is isolated from pineapple plant, Ananas comosus.

See also

References

  1. Sasaki M, Kato T, Iida S (September 1973). "Antigenic determinant common to four kinds of thiol proteases of plant origin". Journal of Biochemistry. 74 (3): 635–7. PMID 4127920.
  2. Yamada F, Takahashi N, Murachi T (June 1976). "Purification and characterization of a proteinase from pineapple fruit, fruit bromelain FA2". Journal of Biochemistry. 79 (6): 1223–34. PMID 956152.
  3. Ota S, Muta E, Katahira Y, Okamoto Y (July 1985). "Reinvestigation of fractionation and some properties of the proteolytically active components of stem and fruit bromelains". Journal of Biochemistry. 98 (1): 219–28. PMID 4044551.
  4. Rowan AD, Buttle DJ, Barrett AJ (March 1990). "The cysteine proteinases of the pineapple plant". The Biochemical Journal. 266 (3): 869–75. PMC 1131219. PMID 2327970.
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