GATAD2B

Transcriptional repressor p66-beta is a protein that in humans is encoded by the GATAD2B gene.[5][6][7]

GATAD2B
Identifiers
AliasesGATAD2B, MRD18, P66beta, p68, GATA zinc finger domain containing 2B, GANDS
External IDsOMIM: 614998 MGI: 2443225 HomoloGene: 32484 GeneCards: GATAD2B
Orthologs
SpeciesHumanMouse
Entrez

57459

229542

Ensembl

ENSG00000143614
ENSG00000261992

ENSMUSG00000042390

UniProt

Q8WXI9

Q8VHR5

RefSeq (mRNA)

NM_020699

NM_139304
NM_001379655
NM_001379656
NM_001379657

RefSeq (protein)

NP_065750

NP_647465
NP_001366584
NP_001366585
NP_001366586

Location (UCSC)Chr 1: 153.79 – 153.92 MbChr 3: 90.2 – 90.27 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse


Interactions

GATAD2B has been shown to interact with Methyl-CpG-binding domain protein 2,[6][8] MBD3,[6][8] RBBP7[6] and RBBP4.[6]

References

  1. ENSG00000261992 GRCh38: Ensembl release 89: ENSG00000143614, ENSG00000261992 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000042390 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Hirosawa M, Nagase T, Ishikawa K, Kikuno R, Nomura N, Ohara O (Jan 2000). "Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain". DNA Res. 6 (5): 329–36. doi:10.1093/dnares/6.5.329. PMID 10574461.
  6. Feng Q, Cao R, Xia L, Erdjument-Bromage H, Tempst P, Zhang Y (Dec 2001). "Identification and functional characterization of the p66/p68 components of the MeCP1 complex". Mol Cell Biol. 22 (2): 536–46. doi:10.1128/MCB.22.2.536-546.2002. PMC 139742. PMID 11756549.
  7. "Entrez Gene: GATAD2B GATA zinc finger domain containing 2B".
  8. Brackertz, Marc; Boeke Joern; Zhang Ru; Renkawitz Rainer (Oct 2002). "Two highly related p66 proteins comprise a new family of potent transcriptional repressors interacting with MBD2 and MBD3". J. Biol. Chem. United States. 277 (43): 40958–66. doi:10.1074/jbc.M207467200. ISSN 0021-9258. PMID 12183469.

Further reading


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