GFRAL

GFRAL
Identifiers
Aliases	GFRAL, C6orf144, GRAL, UNQ9356, bA360D14.1, GDNF family receptor alpha like
External IDs	OMIM: 617837 MGI: 3607786 HomoloGene: 45748 GeneCards: GFRAL
Gene location (Human)
Chr.	Chromosome 6 (human)[1]
End	55,402,493 bp[1]
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)[2]
End	76,120,939 bp[2]
RNA expression pattern
	Top expressed in
	sural nerve; ; right lobe of liver; ; subcutaneous adipose tissue; ; body of pancreas;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	signaling receptor activity; protein binding; glial cell-derived neurotrophic factor receptor activity; receptor tyrosine kinase binding;
Cellular component	integral component of membrane; plasma membrane; intracellular anatomical structure; membrane; external side of plasma membrane; receptor complex;
Biological process	negative regulation of neuron apoptotic process; stress-activated protein kinase signaling cascade; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; reduction of food intake in response to dietary excess; glial cell-derived neurotrophic factor receptor signaling pathway; positive regulation of MAPK cascade; positive regulation of protein kinase B signaling; nervous system development;
	Sources:Amigo / QuickGO
Orthologs
	389400
	404194
	ENSG00000187871
	ENSMUSG00000059383
	Q6UXV0
	Q6SJE0
	NM_207410
	NM_205844
	NP_997293
	NP_995316
	Wikidata
View/Edit Human	View/Edit Mouse

GDNF family receptor alpha like is a protein that in humans is encoded by the GFRAL gene. [5]

References

GRCh38: Ensembl release 89: ENSG00000187871 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000059383 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: GDNF family receptor alpha like". Retrieved 2017-09-04.

Overview of all the structural information available in the PDB for UniProt: Q6UXV0 (GDNF family receptor alpha-like) at the PDBe-KB.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.