GLTP

Glycolipid transfer protein is a protein that in humans is encoded by the GLTP gene.[5][6][7]

GLTP
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesGLTP, glycolipid transfer protein
External IDsOMIM: 608949 MGI: 1929253 HomoloGene: 41133 GeneCards: GLTP
Orthologs
SpeciesHumanMouse
Entrez

51228

56356

Ensembl

ENSG00000139433

ENSMUSG00000011884

UniProt

Q9NZD2

Q9JL62

RefSeq (mRNA)

NM_016433

NM_019821

RefSeq (protein)

NP_057517

NP_062795

Location (UCSC)Chr 12: 109.85 – 109.88 MbChr 5: 114.81 – 114.83 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

The protein encoded by this gene is similar to bovine and porcine proteins which accelerate transfer of certain glycosphingolipids and glyceroglycolipids between membranes. It is thought to be a cytoplasmic protein.[7]

References

  1. GRCh38: Ensembl release 89: ENSG00000139433 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000011884 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Li XM, Malakhova ML, Lin X, Pike HM, Chung T, Molotkovsky JG, Brown RE (Aug 2004). "Human glycolipid transfer protein: probing conformation using fluorescence spectroscopy". Biochemistry. 43 (31): 10285–94. doi:10.1021/bi0495432. PMC 2593833. PMID 15287756.
  6. Malakhova ML, Malinina L, Pike HM, Kanack AT, Patel DJ, Brown RE (Jul 2005). "Point mutational analysis of the liganding site in human glycolipid transfer protein. Functionality of the complex". J Biol Chem. 280 (28): 26312–20. doi:10.1074/jbc.M500481200. PMC 1393170. PMID 15901739.
  7. "Entrez Gene: GLTP glycolipid transfer protein".

Further reading


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