GNA15

GNA15
Identifiers
Aliases	GNA15, GNA16, G protein subunit alpha 15, HG1L
External IDs	OMIM: 139314 MGI: 95770 HomoloGene: 1563 GeneCards: GNA15
Gene location (Human)
Chr.	Chromosome 19 (human)[1]
End	3,163,749 bp[1]
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)[2]
End	81,360,059 bp[2]
RNA expression pattern
	Top expressed in
	palpebral conjunctiva; ; monocyte; ; cavity of mouth; ; skin of abdomen; ; amniotic fluid; ; periodontal fiber; ; blood; ; pancreatic ductal cell; ; vagina; ; mucosa of urinary bladder;
	Top expressed in
	lip; ; esophagus; ; morula; ; zone of skin; ; skin of back; ; thymus; ; cornea; ; superior frontal gyrus; ; entorhinal cortex; ; spleen;
	More reference expression data
	n/a
Gene ontology
Molecular function	guanyl nucleotide binding; nucleotide binding; GTP binding; metal ion binding; GTPase activity; G-protein beta/gamma-subunit complex binding; G protein-coupled receptor binding; signal transducer activity;
Cellular component	plasma membrane; heterotrimeric G-protein complex;
Biological process	platelet activation; phospholipase C-activating G protein-coupled receptor signaling pathway; phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway; phospholipase C-activating dopamine receptor signaling pathway; activation of phospholipase C activity; signal transduction; adenylate cyclase-modulating G protein-coupled receptor signaling pathway; G protein-coupled receptor signaling pathway; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	2769
	14676
	ENSG00000060558
	ENSMUSG00000034792
	P30679
	P30678
	NM_002068
	NM_010304
	NP_002059
	NP_034434
	Wikidata
View/Edit Human	View/Edit Mouse

Guanine nucleotide-binding protein subunit alpha-15 is a protein that in humans is encoded by the GNA15 gene.[5][6][7] G₁₅α is a member of the Gq alpha subunit family, and functions as a constituent of a heterotrimeric G protein in cell signal transduction. It was also previously known as G₁₆α.[5]

References

GRCh38: Ensembl release 89: ENSG00000060558 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000034792 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Wilkie TM, Gilbert DJ, Olsen AS, Chen XN, Amatruda TT, Korenberg JR, Trask BJ, de Jong P, Reed RR, Simon MI, et al. (Jun 1993). "Evolution of the mammalian G protein alpha subunit multigene family". Nat Genet. 1 (2): 85–91. doi:10.1038/ng0592-85. PMID 1302014. S2CID 31888533.
"Entrez Gene: GNA15 G protein subunit alpha 15 [ Homo sapiens (human) ]". Retrieved 2019-07-25.
GUANINE NUCLEOTIDE-BINDING PROTEIN, ALPHA-15; GNA15 at OMIM. Retrieved JULY 25, 2019.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000060558 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000034792 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1302014-5] Wilkie TM, Gilbert DJ, Olsen AS, Chen XN, Amatruda TT, Korenberg JR, Trask BJ, de Jong P, Reed RR, Simon MI, et al. (Jun 1993). "Evolution of the mammalian G protein alpha subunit multigene family". Nat Genet. 1 (2): 85–91. doi:10.1038/ng0592-85. PMID 1302014. S2CID 31888533.

[entrez-6] "Entrez Gene: GNA15 G protein subunit alpha 15 [ Homo sapiens (human) ]". Retrieved 2019-07-25.

[7] GUANINE NUCLEOTIDE-BINDING PROTEIN, ALPHA-15; GNA15 at OMIM. Retrieved JULY 25, 2019.

GNA15

See also

References