GREB1

Growth regulation by estrogen in breast cancer 1 is a protein that in humans is encoded by the GREB1 gene.[5]

GREB1
Identifiers
AliasesGREB1, growth regulation by estrogen in breast cancer 1, growth regulating estrogen receptor binding 1
External IDsOMIM: 611736 MGI: 2149712 HomoloGene: 8780 GeneCards: GREB1
Orthologs
SpeciesHumanMouse
Entrez

9687

268527

Ensembl

ENSG00000196208

ENSMUSG00000036523

UniProt

Q4ZG55

Q3UHK3

RefSeq (mRNA)

NM_014668
NM_033090
NM_148903

NM_001252071
NM_015764

RefSeq (protein)

NP_055483
NP_149081
NP_683701

NP_001239000
NP_056579

Location (UCSC)Chr 2: 11.48 – 11.64 MbChr 12: 16.72 – 16.85 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

This gene is an estrogen-responsive gene that is an early response gene in the estrogen receptor-regulated pathway. It is thought to play an important role in hormone-responsive tissues and cancer. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[5]

References

  1. GRCh38: Ensembl release 89: ENSG00000196208 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000036523 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Growth regulation by estrogen in breast cancer 1".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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