GRWD1

Glutamate-rich WD repeat-containing protein 1 is a WD40 repeat protein that in humans is encoded by the GRWD1 gene. It localizes to the nucleus and has known functions in regulating chromatin openness and loading of MCM helicase.[5][6]

GRWD1
Identifiers
AliasesGRWD1, CDW4, GRWD, RRB1, WDR28, glutamate-rich WD repeat containing 1, glutamate rich WD repeat containing 1
External IDsOMIM: 610597 MGI: 2141989 HomoloGene: 6644 GeneCards: GRWD1
Orthologs
SpeciesHumanMouse
Entrez

83743

101612

Ensembl

ENSG00000105447

ENSMUSG00000053801

UniProt

Q9BQ67

Q810D6

RefSeq (mRNA)

NM_031485

NM_153419

RefSeq (protein)

NP_113673

NP_700468

Location (UCSC)Chr 19: 48.45 – 48.46 MbChr 7: 45.47 – 45.48 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

References

  1. GRCh38: Ensembl release 89: ENSG00000105447 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000053801 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Gratenstein K, Heggestad AD, Fortun J, Notterpek L, Pestov DG, Fletcher BS (Jun 2005). "The WD-repeat protein GRWD1: potential roles in myeloid differentiation and ribosome biogenesis". Genomics. 85 (6): 762–73. doi:10.1016/j.ygeno.2005.02.010. PMID 15885502.
  6. "Entrez Gene: GRWD1 glutamate-rich WD repeat containing 1".

Further reading

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.