GTPBP1

GTP-binding protein 1 is a protein that in humans is encoded by the GTPBP1 gene.[5][6]

GTPBP1
Identifiers
AliasesGTPBP1, GP-1, GP1, HSPC018, GTP binding protein 1
External IDsOMIM: 602245 MGI: 109443 HomoloGene: 3165 GeneCards: GTPBP1
Orthologs
SpeciesHumanMouse
Entrez

9567

14904

Ensembl

ENSG00000100226

ENSMUSG00000042535

UniProt

O00178

O08582

RefSeq (mRNA)

NM_004286

NM_013818

RefSeq (protein)

NP_004277

NP_038846

Location (UCSC)Chr 22: 38.71 – 38.74 MbChr 15: 79.58 – 79.61 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene is upregulated by interferon-gamma and encodes a protein that is a member of the AGP11/GTPBP1 family of GTP-binding proteins. A structurally similar protein has been found in mice, where disruption of the gene for that protein had no observable phenotype.[6]

References

  1. GRCh38: Ensembl release 89: ENSG00000100226 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000042535 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Senju S, Nishimura Y (Apr 1997). "Identification of human and mouse GP-1, a putative member of a novel G-protein family". Biochem Biophys Res Commun. 231 (2): 360–4. doi:10.1006/bbrc.1997.6103. PMID 9070279.
  6. "Entrez Gene: GTPBP1 GTP binding protein 1".

Further reading


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