Gaba type a receptor associated protein like 1
GABA type A receptor associated protein like 1 is a protein that in humans is encoded by the GABARAPL1 gene. [5]
| GABARAPL1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | GABARAPL1, APG8-LIKE, APG8L, ATG8, ATG8B, ATG8L, GEC1, GABA type A receptor associated protein like 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 607420 MGI: 1914980 HomoloGene: 134420 GeneCards: GABARAPL1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
References
- GRCh38: Ensembl release 89: ENSG00000139112 - Ensembl, May 2017
- GRCm38: Ensembl release 89: ENSMUSG00000030161 - Ensembl, May 2017
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Entrez Gene: GABA type A receptor associated protein like 1". Retrieved 2017-12-21.
Further reading
- Nemos C, Mansuy V, Vernier-Magnin S, Fraichard A, Jouvenot M, Delage-Mourroux R (2003). "Expression of gec1/GABARAPL1 versus GABARAP mRNAs in human: predominance of gec1/GABARAPL1 in the central nervous system". Brain Res. Mol. Brain Res. 119 (2): 216–9. doi:10.1016/j.molbrainres.2003.09.011. PMID 14625090.
- Chen C, Li JG, Chen Y, Huang P, Wang Y, Liu-Chen LY (2006). "GEC1 interacts with the kappa opioid receptor and enhances expression of the receptor". J. Biol. Chem. 281 (12): 7983–93. doi:10.1074/jbc.M509805200. PMID 16431922.
- Chen Y, Chen C, Kotsikorou E, Lynch DL, Reggio PH, Liu-Chen LY (2009). "GEC1-kappa opioid receptor binding involves hydrophobic interactions: GEC1 has chaperone-like effect". J. Biol. Chem. 284 (3): 1673–85. doi:10.1074/jbc.M808303200. PMC 2615498. PMID 19001416.
- Betin VM, Lane JD (2009). "Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis". J. Cell Sci. 122 (Pt 14): 2554–66. doi:10.1242/jcs.046250. PMC 2704886. PMID 19549685.
- Berthier A, Seguin S, Sasco AJ, Bobin JY, De Laroche G, Datchary J, Saez S, Rodriguez-Lafrasse C, Tolle F, Fraichard A, Boyer-Guittaut M, Jouvenot M, Delage-Mourroux R, Descotes F (2010). "High expression of gabarapl1 is associated with a better outcome for patients with lymph node-positive breast cancer". Br. J. Cancer. 102 (6): 1024–31. doi:10.1038/sj.bjc.6605568. PMC 2844027. PMID 20197771.
- Johnatty SE, Beesley J, Chen X, Macgregor S, Duffy DL, Spurdle AB, deFazio A, Gava N, Webb PM, Rossing MA, Doherty JA, Goodman MT, Lurie G, Thompson PJ, Wilkens LR, Ness RB, Moysich KB, Chang-Claude J, Wang-Gohrke S, Cramer DW, Terry KL, Hankinson SE, Tworoger SS, Garcia-Closas M, Yang H, Lissowska J, Chanock SJ, Pharoah PD, Song H, Whitemore AS, Pearce CL, Stram DO, Wu AH, Pike MC, Gayther SA, Ramus SJ, Menon U, Gentry-Maharaj A, Anton-Culver H, Ziogas A, Hogdall E, Kjaer SK, Hogdall C, Berchuck A, Schildkraut JM, Iversen ES, Moorman PG, Phelan CM, Sellers TA, Cunningham JM, Vierkant RA, Rider DN, Goode EL, Haviv I, Chenevix-Trench G (2010). "Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot"". PLOS Genet. 6 (7): e1001016. doi:10.1371/journal.pgen.1001016. PMC 2900295. PMID 20628624.
- Le Grand JN, Chakrama FZ, Seguin-Py S, Fraichard A, Delage-Mourroux R, Jouvenot M, Boyer-Guittaut M (2011). "GABARAPL1 (GEC1): original or copycat?". Autophagy. 7 (10): 1098–107. doi:10.4161/auto.7.10.15904. PMID 21597319.
- Rozenknop A, Rogov VV, Rogova NY, Löhr F, Güntert P, Dikic I, Dötsch V (2011). "Characterization of the interaction of GABARAPL-1 with the LIR motif of NBR1". J. Mol. Biol. 410 (3): 477–87. doi:10.1016/j.jmb.2011.05.003. PMID 21620860.
- Jiang S, Wells CD, Roach PJ (2011). "Starch-binding domain-containing protein 1 (Stbd1) and glycogen metabolism: Identification of the Atg8 family interacting motif (AIM) in Stbd1 required for interaction with GABARAPL1". Biochem. Biophys. Res. Commun. 413 (3): 420–5. doi:10.1016/j.bbrc.2011.08.106. PMC 3411280. PMID 21893048.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.