Gaetano Ciancio

Gaetano Ciancio is an Italian American surgeon at the University of Miami who specializes in kidney transplant. He is the chief medical and academic officer of the Miami Transplant Institute and the director of its Kidney & Kidney-Pancreas Programs.[1] His most significant contributions to medicine are related to surgically treating kidney cancer once it has spread to the inferior vena cava[2][3] and in optimizing the immunosuppression protocol after kidney transplant.[4]

Gaetano Ciancio
Born
Roccapiemonte, Italy
EducationMD (1982), MBA (2001)
Alma materUniversidad Central De Venezuela, Jackson Memorial Hospital
Occupation(s)Transplant Surgeon, Urologic Oncologist

Life

Ciancio was born on June 15, 1956, in Roccapiemonte, Italy. He received his Doctor of Medicine from Central University of Venezuela, then completed his residency at Jackson Memorial Hospital,[1][5] followed by completing a fellowship in multiorgan transplant surgery.[5]

Research

Large Kidney Tumors

Ciancio developed techniques for the surgical resection of large kidney tumors.[6] His results demonstrated that by performing a liver mobilization, urological oncologists could avoid a thoracic incision in many patients [7]

Inferior Vena Cava Thrombectomy

Building on the techniques described for resecting large renal tumors, Ciancio adapted his liver mobilization technique to address retrohepatic or even suprahepatic inferior vena caval thrombus associated with renal tumors.[3]

Together with his long time collaborator Mark Soloway, they published a step-by-step guide toward resecting renal cell carcinoma with associated inferior vena cava thrombus.[8]

Immunosuppression

Ciancio helped develop and popularize alternative immunosuppression regimens which successfully lowered the dose of immunosuppressants without increasing organ rejection.[9][10][11]

Reconstruction During Kidney Transplant

During kidney transplantation, the most common arterial reconstruction is for a single renal artery to be anastomosed to the external iliac artery.[12][13] Ciancio has popularized several techniques for dealing with anatomical variations, including the usage of the inferior epigastric artery to anastomose to a small upper-pole artery.[14]

Additionally, Ciancio has been part of the Miami Transplant Team that developed the bladder patch technique, where for various indications the kidney together with the ureter and some amount of donor bladder are transplanted en-bloc.[15]

Pancreatic Transplantation

Together with George Burke, Ciancio has made contributions to the field of pancreas transplantations both regarding management of surgical complications and immunosuppression strategies, including publishing a technique for thrombectomy for complete venous thrombosis of the transplanted pancreas.[16]

Awards and honors
Ciancio taking Ali Mouzannar (Urology Resident) through a living related kidney transplant

In 2013, he served as President of the Urologic Society for Transplantation and Renal Surgery.[17] He was knighted in Italy by Sergio Mattarella and is a member of the Order of Merit of the Italian Republic[18]

Bibliography

He is an author or co-author of 2 books, 30 book chapters and over 388 peer-reviewed articles published in medical journals for topics involving the field of solid organ transplantation and urologic oncology.[19]

References
  1. "Gaetano Ciancio". Jackson Health System. Retrieved 29 December 2020.
  2. Ciancio, Gaetano; Vaidya, Anil; Savoie, Mark; Soloway, Mark (2002). "Management of Renal Cell Carcinoma With Level III Thrombus in the Inferior Vena Cava". Journal of Urology. Ovid Technologies (Wolters Kluwer Health). 168 (4 Part 1): 1374–1377. doi:10.1016/s0022-5347(05)64452-7. ISSN 0022-5347. PMID 12352396.
  3. Ciancio, Gaetano; Livingstone, Alan S.; Soloway, Mark (2007). "Surgical Management of Renal Cell Carcinoma with Tumor Thrombus in the Renal and Inferior Vena Cava: The University of Miami Experience in Using Liver Transplantation Techniques". European Urology. Elsevier BV. 51 (4): 988–995. doi:10.1016/j.eururo.2006.11.055. ISSN 0302-2838. PMID 17175095.
  4. Ciancio, Gaetano; Burke, George W.; Gaynor, Jeffrey J.; Carreno, Manuel R.; Cirocco, Robert E.; Mathew, James M.; Mattiazzi, Adela; Cordovilla, Tatiana; Roth, David; Kupin, Warren; Rosen, Anne; Esquenazi, Violet; Tzakis, Andreas G.; Miller, Joshua (2005). "A Randomized Trial of Three Renal Transplant Induction Antibodies: Early Comparison of Tacrolimus, Mycophenolate Mofetil, and Steroid Dosing, and Newer Immune-Monitoring1". Transplantation. Ovid Technologies (Wolters Kluwer Health). 80 (4): 457–465. doi:10.1097/01.tp.0000165847.05787.08. ISSN 0041-1337. PMID 16123718. S2CID 1958705.
  5. "Dr. Gaetano Ciancio MD". Retrieved 2021-06-06.
  6. Ciancio G, Hawke C, Soloway M (2000). "The use of liver transplant techniques to aid in the surgical management of urological tumors". J Urol. 164 (3 Pt 1): 665–72. doi:10.1097/00005392-200009010-00012. PMID 10953122.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  7. Ciancio, Gaetano; Manoharan, Murugesan; Katkoori, Devendar; De Los Santos, Rosely; Soloway, Mark S. (2010). "Long-term Survival in Patients Undergoing Radical Nephrectomy and Inferior Vena Cava Thrombectomy: Single-Center Experience". European Urology. Elsevier BV. 57 (4): 667–672. doi:10.1016/j.eururo.2009.06.009. ISSN 0302-2838. PMID 19560258.
  8. Ciancio, Gaetano; Gonzalez, Javier; Shirodkar, Samir P.; Angulo, Javier C.; Soloway, Mark S. (2011). "Liver Transplantation Techniques for the Surgical Management of Renal Cell Carcinoma with Tumor Thrombus in the Inferior Vena Cava: Step-by-Step Description". European Urology. Elsevier BV. 59 (3): 401–406. doi:10.1016/j.eururo.2010.07.028. ISSN 0302-2838. PMID 20724064.
  9. Ciancio, Gaetano; Burke, George W.; Gaynor, Jeffrey J.; Mattiazzi, Adela; Roth, David; Kupin, Warren; Nicolas, Maud; Ruiz, Phillip; Rosen, Anne; Miller, Joshua (2004). "A randomized long-term trial of tacrolimus/sirolimus versus tacrolimus/mycophenolate mofetil versus cyclosporine (NEORAL)/sirolimus in renal transplantation. Ii. Survival, function, and protocol compliance at 1 year". Transplantation. Ovid Technologies (Wolters Kluwer Health). 77 (2): 252–258. doi:10.1097/01.tp.0000101495.22734.07. ISSN 0041-1337. PMID 14742990. S2CID 31764876.
  10. Ciancio, Gaetano; Burke, George W.; Gaynor, Jeffrey J.; Mattiazzi, Adela; Roohipour, Ramin; Carreno, Manuel R.; Roth, David; Ruiz, Phillip; Kupin, Warren; Rosen, Anne; Esquenazi, Violet; Tzakis, Andreas G.; Miller, Joshua (2004). "The Use of Campath-1H as Induction Therapy in Renal Transplantation: Preliminary Results". Transplantation. Ovid Technologies (Wolters Kluwer Health). 78 (3): 426–433. doi:10.1097/01.tp.0000128625.29654.eb. ISSN 0041-1337. PMID 15316372. S2CID 24331532.
  11. Ciancio G, Burke GW, Suzart K, Roth D, Kupin W, Rosen A; et al. (2002). "Daclizumab induction, tacrolimus, mycophenolate mofetil and steroids as an immunosuppression regimen for primary kidney transplant recipients". Transplantation. 73 (7): 1100–6. doi:10.1097/00007890-200204150-00015. PMID 11965039. S2CID 46141107.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  12. Benoit G (1996). "[Surgical technics of kidney transplantation]". Prog Urol (in French). 6 (4): 594–604. PMID 8924941.
  13. Coen, L. D.; Raftery, A. T. (1992). "Anatomical variations of the renal arteries and renal transplantation". Clinical Anatomy. Wiley. 5 (6): 425–432. doi:10.1002/ca.980050602. ISSN 0897-3806. S2CID 74028141.
  14. Moon, Jang IL; Ciancio, Gaetano; Burke, George W (2005). "Arterial reconstruction with donor iliac vessels during pancreas transplantation: an intraoperative approach to arterial injury or inadequate flow". Clinical Transplantation. Wiley. 19 (2): 286–290. doi:10.1111/j.1399-0012.2005.00339.x. ISSN 0902-0063. PMID 15740569. S2CID 25431215.
  15. Kato, T.; Selvaggi, G.; Burke, G.; Ciancio, G.; Zilleruelo, G.; Hattori, M.; Gosalbez, R.; Tzakis, A. (2008). "Partial Bladder Transplantation with En Bloc Kidney Transplant—The First Case Report of a 'Bladder Patch Technique' in a Human". American Journal of Transplantation. 8 (5): 1060–1063. doi:10.1111/j.1600-6143.2008.02180.x. ISSN 1600-6135. PMID 18312611. S2CID 205844631.
  16. Ciancio G, Julian JF, Fernandez L, Miller J, Burke GW (2000). "Successful surgical salvage of pancreas allografts after complete venous thrombosis". Transplantation. 70 (1): 126–31. PMID 10919588.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  17. "Dr. Gaetano Ciancio Recognized for Excellence in Adult Organ Transplantation". 24-7 Press Release Newswire. 7 April 2015. Retrieved 29 December 2020.
  18. "2021 ASTS Recognition Award Recipients". Retrieved 2021-03-05.
  19. "2021 ASTS Recognition Award Recipients Francis Moore Excellence in Mentorship in the Field of Transplantation Surgery Award". Retrieved 2021-06-06.
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