Ganoderol

Ganoderols are triterpenes isolated from Ganoderma lucidum.[1][2]

Ganoderol

Ganoderol A (top) and ganoderol B
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
  • (A): InChI=1S/C30H46O2/c1-20(19-31)9-8-10-21(2)22-13-17-30(7)24-11-12-25-27(3,4)26(32)15-16-28(25,5)23(24)14-18-29(22,30)6/h9,11,14,21-22,25,31H,8,10,12-13,15-19H2,1-7H3/b20-9+
    Key: QWFPQDGDUOGOJF-AWQFTUOYSA-N
  • (B): InChI=1S/C30H48O2/c1-20(19-31)9-8-10-21(2)22-13-17-30(7)24-11-12-25-27(3,4)26(32)15-16-28(25,5)23(24)14-18-29(22,30)6/h9,11,14,21-22,25-26,31-32H,8,10,12-13,15-19H2,1-7H3/b20-9+/t21-,22-,25+,26+,28-,29-,30+/m1/s1
    Key: AOXXVRDKZLRGTJ-AZIDVCJLSA-N
  • (A): CC(CC/C=C(\C)/CO)C1CCC2(C1(CC=C3C2=CCC4C3(CCC(=O)C4(C)C)C)C)C
  • (B): C[C@H](CC/C=C(\C)/CO)[C@H]1CC[C@@]2([C@@]1(CC=C3C2=CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)C)C
Properties
C30H46O2 (A)
C30H48O2 (B)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References

  1. Fatmawati, S; Shimizu, K; Kondo, R (2011). "Ganoderol B: A potent α-glucosidase inhibitor isolated from the fruiting body of Ganoderma lucidum". Phytomedicine. 18 (12): 1053–5. doi:10.1016/j.phymed.2011.03.011. PMID 21596546.
  2. Liu, J; Shimizu, K; Konishi, F; Kumamoto, S; Kondo, R (2007). "The anti-androgen effect of ganoderol B isolated from the fruiting body of Ganoderma lucidum". Bioorganic & Medicinal Chemistry. 15 (14): 4966–72. doi:10.1016/j.bmc.2007.04.036. PMID 17499997.


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