Gelesis

Gelesis is a biotechnology company located in Boston, Massachusetts that developed the weight loss device Gelesis100 (Plenity) for use in overweight and obesity. The company produces Gelesis100, which is a superabsorbent hydrogel capsule that expands in the stomach, creating a feeling of fullness, helping people reduce the amount of food they eat.[1][2] The company was founded in 2006 to develop medical devices and treatments for obesity.[3]

Gelesis
TypePrivate
NYSE: GLS
IndustryHealthcare, Biotechnology
Founded2006
Headquarters
Key people
John LaMattina, PhD – Chairman, Yishai Zohar - CEO and Founder, David Pass, PharmD – Chief Operating Officer
Websitewww.gelesis.com

History

Gelesis was founded by PureTech Ventures, a life sciences venture firm based in Boston,[3][1] and ExoTech Bio, an Israel-based research and development company.[4] The company operates as an affiliate of PureTech Health.[5][6] Former PureTech Ventures partner Yishai Zohar co-founded the company and served as CEO.[4]

The company's technology was co-invented by Alessandro Sannino, a professor of engineering at the University of Salento, who had been researching the idea prior to the launch of Gelesis.[1]

In January 2008, the company raised $16 million in its first financing round, led by OrbiMed Advisors and Queensland BioCapital Funds.[4]

In 2010, the company passed the first human trials of its treatment.[1][7] The company’s product was originally called Attiva, but was later renamed Gelesis100.[8]

In 2014, Gelesis raised $12 million in its fifth funding round, bringing its total funding to $42 million.[9][10]

In March 2015, the company closed a $22 million funding round.[11] In April 2015, the company announced an initial public offering (IPO) for $60 million,[12] but pulled out later that year.[13][14] In December 2015, Gelesis raised $31.5 million shortly after cancelling its IPO.[15][14]

In 2018, Gelesis raised $30 million in preparation for regulatory submissions in the U.S. and Europe and initial marketing of Gelesis100.[16][17]

In January 2022, the company completed a business combination with Capstar Special Purpose Acquisition Corp. and commenced trading on the New York Stock Exchange under the ticker symbol “GLS."[18]

References

  1. Timmerman, Luke (April 22, 2010). "Obesity Capsule From Gelesis, Made to Swell Up in the Stomach, Passes First Human Trial". Xconomy.
  2. "Early Results Arrive on Weight-Loss Pills That Expand in the Stomach". Retrieved 2018-09-28.
  3. "Gelesis raises $12 million for pill that staves off hunger". BetaBoston.com. May 16, 2014.
  4. "Xconomy: Obesity Startup Gelesis Gobbles Up $16M in Financing". Xconomy. 2008-01-03. Retrieved 2018-09-28.
  5. Letter, The Pharma. "Gelesis raises $30 million to fund novel weight loss therapy". www.thepharmaletter.com. Retrieved 2018-09-28.
  6. Reuters Editorial. "PureTech's Gelesis says obesity drug achieved weight loss in study". U.S. Retrieved 2018-09-28. {{cite news}}: |author= has generic name (help)
  7. "Anti-Obesity Pill Swells in Your Stomach, Making You Full Before You Even Start Eating". Popular Science. Retrieved 2018-09-28.
  8. "Hydrogel 'smart pill' shows promise as weight loss aid". Medical News Today. Retrieved 2018-09-28.
  9. "The Daily Startup: Medtronic Spinout Raises $40M to Treat Sleep Apnea". WSJ.com. May 16, 2014.
  10. "Xconomy: Gelesis Resurfaces With $12M, Preps First Weight Loss Data". Xconomy. 2014-05-16. Retrieved 2018-09-27.
  11. "Boston weight-loss biotech Gelesis raises $22M". www.bizjournals.com. Retrieved 2018-09-28.
  12. "Term Sheet -- Thursday, April 2". Fortune. Retrieved 2018-09-28.
  13. "Company with obesity treatment raises $31.5M on heels of withdrawn IPO". www.bizjournals.com. Retrieved 2018-09-28.
  14. "Gelesis drops IPO, raises $31.5M for pivotal U.S. trial of hydrogel weight-loss capsule | FierceBiotech". www.fiercebiotech.com. Retrieved 2018-09-28.
  15. "Xconomy: Months After Postponed IPO, Gelesis Nabs $31.5M And a New Investor". Xconomy. 2015-12-18. Retrieved 2018-09-28.
  16. Herper, Matthew. "In Two Months, Biotech Startups Raised More Money Than In All Of 2013". Forbes. Retrieved 2018-03-05.
  17. "Gelesis raises $30M to gear up for weight loss launch | FierceBiotech". www.fiercebiotech.com. Retrieved 2018-03-05.
  18. "Gelesis®, the Maker of Plenity® for Weight Management, Will Debut as a Publicly Traded Company Following the Closing of Its Business Combination with Capstar". ir.gelesis.com. Retrieved 2022-01-18.
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