Gene-activated matrix

In gene-activated matrix technology (GAM), cytokines and growth factors could be delivered not as recombinant proteins but as plasmid genes.[1] GAM is one of the tissue engineering approaches to wound healing. Following gene delivery, the recombinant cytokine could be expressed in situ by endogenous would healing cells – in small amounts but for a prolonged period of time – leading to reproducible tissue regeneration.

References

Bonadio, Jeffrey (2000). "Review: Local Gene Delivery for Tissue Regeneration". E-biomed: The Journal of Regenerative Medicine. 1 (2): 25–29. doi:10.1089/152489000414552.

External links

Cardium Presents Gene Activated Matrix Technology And Update On Excellarate Clinical Development Program At ASGT Annual Meeting

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[1] Bonadio, Jeffrey (2000). "Review: Local Gene Delivery for Tissue Regeneration". E-biomed: The Journal of Regenerative Medicine. 1 (2): 25–29. doi:10.1089/152489000414552.