Glutaconate CoA-transferase
In enzymology, a glutaconate CoA-transferase (EC 2.8.3.12) is an enzyme that catalyzes the chemical reaction
- acetyl-CoA + (E)-glutaconate acetate + glutaconyl-1-CoA
| glutaconate CoA-transferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.8.3.12 | ||||||||
| CAS no. | 79078-99-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are acetyl-CoA and (E)-glutaconate, whereas its two products are acetate and glutaconyl-1-CoA.
This enzyme belongs to the family of transferases, specifically the CoA-transferases. The systematic name of this enzyme class is acetyl-CoA:(E)-glutaconate CoA-transferase. This enzyme participates in styrene degradation and butanoate metabolism.
References
- Buckel W, Dorn U, Semmler R (1981). "Glutaconate CoA-transferase from Acidaminococcus fermentans". Eur. J. Biochem. 118 (2): 315–21. doi:10.1111/j.1432-1033.1981.tb06404.x. PMID 6945182.
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