GLRX

Glutaredoxin-1 is a protein that in humans is encoded by the GLRX gene.[5][6]

GLRX
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesGLRX, GRX, GRX1, glutaredoxin
External IDsOMIM: 600443 MGI: 2135625 HomoloGene: 37566 GeneCards: GLRX
Orthologs
SpeciesHumanMouse
Entrez

2745

93692

Ensembl

ENSG00000173221

ENSMUSG00000021591

UniProt

P35754

Q9QUH0

RefSeq (mRNA)

NM_002064
NM_001118890
NM_001243658
NM_001243659

NM_053108
NM_001360151

RefSeq (protein)

NP_001112362
NP_001230587
NP_001230588
NP_002055

NP_444338
NP_001347080

Location (UCSC)Chr 5: 95.75 – 95.82 MbChr 13: 75.99 – 76 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

GLRX has been shown to interact with Wilson disease protein[7] and ATP7A.[7]

References

  1. GRCh38: Ensembl release 89: ENSG00000173221 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000021591 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Padilla CA, Bajalica S, Lagercrantz J, Holmgren A (Feb 1997). "The gene for human glutaredoxin (GLRX) is localized to human chromosome 5q14". Genomics. 32 (3): 455–7. doi:10.1006/geno.1996.0141. PMID 8838810.
  6. "Entrez Gene: GLRX glutaredoxin (thioltransferase)".
  7. Lim, Chris M; Cater Michael A; Mercer Julian F B; La Fontaine Sharon (Sep 2006). "Copper-dependent interaction of glutaredoxin with the N termini of the copper-ATPases (ATP7A and ATP7B) defective in Menkes and Wilson diseases". Biochem. Biophys. Res. Commun. 348 (2): 428–36. doi:10.1016/j.bbrc.2006.07.067. hdl:10536/DRO/DU:30003772. ISSN 0006-291X. PMID 16884690.

Further reading

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.