Golgin a7

GOLGA7
Identifiers
Aliases	GOLGA7, GCP16, GOLGA3AP1, GOLGA7A, HSPC041, golgin A7
External IDs	OMIM: 609453 MGI: 1931029 HomoloGene: 9385 GeneCards: GOLGA7
Gene location (Human)
Chr.	Chromosome 8 (human)[1]
End	41,510,980 bp[1]
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)[2]
End	23,747,090 bp[2]
RNA expression pattern
	Top expressed in
	inferior ganglion of vagus nerve; ; corpus callosum; ; superior vestibular nucleus; ; spinal cord; ; optic nerve; ; subthalamic nucleus; ; ventral tegmental area; ; secondary oocyte; ; substantia nigra; ; pons;
	Top expressed in
	neural tube; ; ganglionic eminence; ; pons; ; stomach; ; medulla oblongata; ; olfactory bulb; ; esophagus; ; spinal cord; ; mesencephalon; ; lip;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; protein-cysteine S-palmitoyltransferase activity;
Cellular component	palmitoyltransferase complex; Golgi membrane; Golgi stack; Golgi apparatus; intrinsic component of Golgi membrane; extracellular exosome; membrane; extracellular region; tertiary granule lumen;
Biological process	peptidyl-L-cysteine S-palmitoylation; protein stabilization; Golgi to plasma membrane protein transport; protein targeting to membrane; neutrophil degranulation;
	Sources:Amigo / QuickGO
Orthologs
	51125
	57437
	ENSG00000147533
	ENSMUSG00000015341
	Q7Z5G4
	Q91W53
	NM_016099; NM_001002296; NM_001174124
	NM_001042484; NM_020585
	NP_001002296; NP_001167595; NP_057183; NP_001349908; NP_001349909
	NP_001035949; NP_065610
	Wikidata
View/Edit Human	View/Edit Mouse

Golgin A7 is a protein that in humans is encoded by the GOLGA7 gene. [5] It is an acylated Golgi protein that interacts with GCP170 protein.[6]

Gene

The protein is 137 amino acids long.[7]

GRCh38: Ensembl release 89: ENSG00000147533 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000015341 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: Golgin A7". Retrieved 2017-05-24.
Ohta E, Misumi Y, Sohda M, Fujiwara T, Yano A, Ikehara Y. Identification and characterization of GCP16, a novel acylated Golgi protein that interacts with GCP170. J Biol Chem. 2003;278(51):51957‐51967. doi:10.1074/jbc.M310014200
"GOLGA7 Gene - GeneCards | GOGA7 Protein | GOGA7 Antibody".

Ohta E, Misumi Y, Sohda M, Fujiwara T, Yano A, Ikehara Y (2003). "Identification and characterization of GCP16, a novel acylated Golgi protein that interacts with GCP170". J. Biol. Chem. 278 (51): 51957–67. doi:10.1074/jbc.M310014200. PMID 14522980.
Swarthout JT, Lobo S, Farh L, Croke MR, Greentree WK, Deschenes RJ, Linder ME (2005). "DHHC9 and GCP16 constitute a human protein fatty acyltransferase with specificity for H- and N-Ras". J. Biol. Chem. 280 (35): 31141–8. doi:10.1074/jbc.M504113200. PMID 16000296.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD (2009). "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip". Am. J. Hum. Genet. 85 (5): 628–42. doi:10.1016/j.ajhg.2009.10.014. PMC 2775832. PMID 19913121.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.