Gomisin A

Gomisin A is a bio-active compound isolated from Schisandra chinensis.[1][2]

Gomisin A
Names
Preferred IUPAC name
(6S,7S)-1,2,3,13-Tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydro-11H-benzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-6-ol
Other names
Besigomsin; Schisandrol B; Schizandrol B
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
UNII
  • InChI=1S/C23H28O7/c1-12-7-13-8-16-20(30-11-29-16)22(28-6)17(13)18-14(10-23(12,2)24)9-15(25-3)19(26-4)21(18)27-5/h8-9,12,24H,7,10-11H2,1-6H3/t12-,23-/m0/s1
    Key: ZWRRJEICIPUPHZ-MYODQAERSA-N
  • C[C@H]1CC2=CC3=C(C(=C2C4=C(C(=C(C=C4C[C@]1(C)O)OC)OC)OC)OC)OCO3
Properties
C23H28O7
Molar mass 416.470 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References
  1. Hwang, IN SIK; Kim, JEE EUN; Lee, Yong JU; Kwak, Moon HWA; Choi, Young Hwan; Kang, Byeong Cheol; Hong, JIN TAE; Hwang, DAE Youn (April 2013). "Protective effects of gomisin A isolated from Schisandra chinensis against CCl(4)-induced hepatic and renal injury". Int. J. Mol. Med. 31 (4): 888–98. doi:10.3892/ijmm.2013.1263. PMID 23381504.
  2. Takeda, S; Maemura, S; Sudo, K; Kase, Y; Arai, I; Ohkura, Y; Funo, S; Fujii, Y; Aburada, M; Hosoya, E (Feb 1986). "Effects of gomisin A, a lignan component of Schizandra fruits, on experimental liver injuries and liver microsomal drug-metabolizing enzymes". Nihon Yakurigaku Zasshi (in Japanese). 87 (2): 169–187. doi:10.1254/fpj.87.169. PMID 3699630.


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