HEBP1

Heme binding protein 1 is a protein that in humans is encoded by the HEBP1 gene.[5]

HEBP1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesHEBP1, HBP, HEBP, heme binding protein 1
External IDsOMIM: 605826 MGI: 1333880 HomoloGene: 8407 GeneCards: HEBP1
Orthologs
SpeciesHumanMouse
Entrez

50865

15199

Ensembl

ENSG00000013583

ENSMUSG00000042770

UniProt

Q9NRV9

Q9R257

RefSeq (mRNA)

NM_015987

NM_013546

RefSeq (protein)

NP_057071

NP_038574

Location (UCSC)Chr 12: 12.97 – 13 MbChr 6: 135.11 – 135.18 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

The full-length protein encoded by this gene is an intracellular tetrapyrrole-binding protein. This protein includes a natural chemoattractant peptide of 21 amino acids at the N-terminus, which is a natural ligand for formyl peptide receptor-like receptor 2 (FPRL2) and promotes calcium mobilization and chemotaxis in monocytes and dendritic cells.[5]

References

  1. GRCh38: Ensembl release 89: ENSG00000013583 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000042770 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Heme binding protein 1".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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