HIE-124

HIE-124 is an investigational nonbenzodiazepine drug being researched for its short acting hypnotic effects.[1]

HIE-124
Identifiers
  • Ethyl 8-oxo-6,7-dihydro-5H-[1,3]thiazolo[3,2-a][1,3]diazepine-3-carboxylate
PubChem CID
ChemSpider
UNII
ChEMBL
Chemical and physical data
FormulaC10H12N2O3S
Molar mass240.28 g·mol−1
3D model (JSmol)
  • O=C(C1=CSC(N1CCC2)=NC2=O)OCC
  • InChI=1S/C10H12N2O3S/c1-2-15-9(14)7-6-16-10-11-8(13)4-3-5-12(7)10/h6H,2-5H2,1H3
  • Key:UXGPDPNGDCOQBY-UHFFFAOYSA-N

References
  1. Kadi A, El-Kashef H, Abdel-Aziz A, Hassan G, Tettey J, Grant M, Lehmann J, El-Subbagh H (February 2008). "Synthesis, ultra-short acting hypnotic activity, and metabolic profile of ethyl 8-oxo-5,6,7,8-tetrahydro-thiazolo[3,2-a] [1,3]diazepin-3-carboxylate (HIE-124)". Archiv der Pharmazie. 341 (2): 81–89. doi:10.1002/ardp.200700132. PMID 18214840. S2CID 12263886.


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