HIST1H4J

Histone cluster 1, H4j is a protein that in humans is encoded by the HIST1H4J gene.[5]

H4C11
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesH4C11, H4/e, H4F2iv, H4FE, dJ160A22.2, histone cluster 1, H4j, histone cluster 1 H4 family member j, H4 clustered histone 11, HIST1H4J, H4C5, H4C4, H4C9, H4C12, H4-16, H4C3, H4C13, H4C1, H4C14, H4C15, H4C8, H4C6, H4C2, TEVANED2
External IDsOMIM: 602826 MGI: 2448425 HomoloGene: 134492 GeneCards: H4C11
Orthologs
SpeciesHumanMouse
Entrez

8363

319157

Ensembl

ENSG00000197238

ENSMUSG00000069274

UniProt

P62805

P62806

RefSeq (mRNA)

NM_021968

NM_175655

RefSeq (protein)
Location (UCSC)Chr 6: 27.82 – 27.82 MbChr 13: 23.74 – 23.74 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Jul 2008].[5]

References

  1. GRCh38: Ensembl release 89: ENSG00000197238 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000069274 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Histone cluster 1, H4j". Retrieved 2012-03-12.

Further reading

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