Hedamycin

Hedamycin is a chemical compound with potential antibiotic and anticancer activity.[1]

Hedamycin
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
  • InChI=1S/C41H50N2O11/c1-16-11-22-30(37-28(16)24(44)14-27(53-37)41(6)39(54-41)36-18(3)52-36)35(48)31-29(34(22)47)20(25-13-23(42(7)8)32(45)17(2)50-25)12-21(33(31)46)26-15-40(5,43(9)10)38(49)19(4)51-26/h11-12,14,17-19,23,25-26,32,36,38-39,45-46,49H,13,15H2,1-10H3
    Key: RZOFHOWMWMTHDX-UHFFFAOYSA-N
  • CC1C(C(CC(O1)C2=CC(=C(C3=C2C(=O)C4=C(C3=O)C5=C(C(=C4)C)C(=O)C=C(O5)C6(C(O6)C7C(O7)C)C)O)C8CC(C(C(O8)C)O)(C)N(C)C)N(C)C)O
Properties
C41H50N2O11
Molar mass 746.854 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References

  1. Tu, L. C.; Melendy, T.; Beerman, T. A. (2004). "DNA damage responses triggered by a highly cytotoxic monofunctional DNA alkylator, hedamycin, a pluramycin antitumor antibiotic". Molecular Cancer Therapeutics. 3 (5): 577–585. PMID 15141015.


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