Hericenone

Hericenones is a class of benzaldehydes that are isolates of the fruiting body of Hericium erinaceum (lion's mane mushroom) that promote nerve growth factor synthesis in vitro.[1] [2]

Hericenone C-H

Hericenones
Hericenones
NameIUPAC nameReference
Hericenone A5-[(2E)-3,7-dimethyl-5-oxoocta-2,6-dienyl]-4-hydroxy-6-methoxy-3H-2-benzofuran-1-one[3][4]
Hericenone B6-[(2Z)-3,7-dimethyl-5-oxoocta-2,6-dienyl]-7-hydroxy-5-methoxy-2-(2-phenylethyl)-3H-isoindol-1-one[5][4]
Hericenone C[4-[(2E)-3,7-dimethyl-5-oxoocta-2,6-dienyl]-2-formyl-3-hydroxy-5-methoxyphenyl]methyl hexadecanoate[6][7]
Hericenone D[4-[(2E)-3,7-dimethyl-5-oxoocta-2,6-dienyl]-2-formyl-3-hydroxy-5-methoxyphenyl]methyl octadecanoate[8][7]
Hericenone E[4-[(2E)-3,7-dimethyl-5-oxoocta-2,6-dienyl]-2-formyl-3-hydroxy-5-methoxyphenyl]methyl (9E,12E)-octadeca-9,12-dienoate[7]
Hericenone F[8-formyl-5-methoxy-2-methyl-2-(4-methyl-2-oxopent-3-enyl)-3,4-dihydrochromen-7-yl]methyl hexadecanoate[9][10]
Hericenone G[8-formyl-5-methoxy-2-methyl-2-(4-methyl-2-oxopent-3-enyl)-3,4-dihydrochromen-7-yl]methyl octadecanoate[11][10]
Hericenone H[8-formyl-5-methoxy-2-methyl-2-(4-methyl-2-oxopent-3-enyl)-3,4-dihydrochromen-7-yl]methyl (9E,12E)-octadeca-9,12-dienoate[12][10]
Hericenone I
Hericenone J6-[(2E)-3,7-dimethylocta-2,6-dienyl]-7-hydroxy-5-methoxy-3H-2-benzofuran-1-one[13]
Hericenone K2-(4-hydroxy-4-methyl-2-oxopentyl)-5-methoxy-2-methyl-4,7-dihydro-3H-furo[3,4-h]chromen-9-one[14]

References
  1. Kawagishi, Hirokazu; Ando, Motoharu; Shinba, Kayoko; Sakamoto, Hideki; Yoshida, Satoshi; Ojima, Fumihiro; Ishiguro, Yukio; Ukai, Nobuo; Furukawa, Shoei (1992). "Chromans, hericenones F, G and H from the mushroom Hericium erinaceum". Phytochemistry. 32: 175–178. doi:10.1016/0031-9422(92)80127-Z.
  2. Ma, B-J; Shen, J-W; Yu, H-Y; Ruan, Yuan; Wu, T-T; Zhao, X (Jun 2010). "Hericenones and erinacines: stimulators of nerve growth factor (NGF) biosynthesis in Hericium erinaceus". Mycology. 1 (2): 92–98. doi:10.1080/21501201003735556.
  3. "Hericenone A". PubChem. Retrieved 2021-04-11.
  4. "Hericenone A and B as cytotoxic principles from the mushroom hericium erinaceum". Tetrahedron Letters. 31 (3): 373–376. 1990-01-01. doi:10.1016/S0040-4039(00)94558-1. ISSN 0040-4039. Retrieved 2021-04-11.
  5. "Hericenone B". PubChem. Retrieved 2021-04-11.
  6. "Hericenone C". PubChem. Retrieved 2021-04-11.
  7. Kawagishi, Hirokazu; Ando, Motoharu; Sakamoto, Hideki; Yoshida, Satoshi; Ojima, Fumihiro; Ishiguro, Yukio; Ukai, Nobuo; Furukawa, Shoei (1991-01-01). "Hericenones C, D and E, stimulators of nerve growth factor (NGF)-synthesis, from the mushroom Hericium erinaceum". Tetrahedron Letters. 32 (35): 4561–4564. doi:10.1016/0040-4039(91)80039-9. ISSN 0040-4039. Retrieved 2021-04-11.
  8. "Hericenone D". PubChem. Retrieved 2021-04-11.
  9. "Hericenone F". PubChem. Retrieved 2021-04-11.
  10. Kawagishi, Hirokazu; Ando, Motoharu; Shinba, Kayoko; Sakamoto, Hideki; Yoshida, Satoshi; Ojima, Fumihiro; Ishiguro, Yukio; Ukai, Nobuo; Furukawa, Shoei (1992-12-23). "Chromans, hericenones F, G and H from the mushroom Hericium erinaceum". Phytochemistry. 32 (1): 175–178. doi:10.1016/0031-9422(92)80127-Z. ISSN 0031-9422. Retrieved 2021-04-11.
  11. "Hericenone G". PubChem. Retrieved 2021-04-11.
  12. "Hericenone H". PubChem. Retrieved 2021-04-11.
  13. "Hericenone J". PubChem. Retrieved 2021-04-12.
  14. "Hericenone K". PubChem. Retrieved 2021-04-12.


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