Holly Brown-Borg

Holly Brown-Borg is an American biologist and biogerontologist best known for her research on the regulation of lifespan by growth hormone. She is the Chester Fritz Distinguished Professor of Pharmacology, Physiology & Therapeutics at the University of North Dakota School of Medicine and Health Sciences.

Education and training

Brown-Borg attended the University of Nebraska-Lincoln as an undergraduate, receiving a B.S. in Agriculture and an M.S. in Animal Science.[1][2] She performed her Ph.D. research at North Carolina State University, followed by post-doctoral research at the USDA Meat Animal Research Center and Southern Illinois University.[3]

Academic career

Brown-Borg joined the faculty of the University of North Dakota School of Medicine and Health Sciences in the Department of Pharmacology, Physiology & Therapeutics as an Assistant Professor in 1995 and was tenured as Associate Professor in 2002. In 2010, Brown-Borg was selected as a Chester Fritz Distinguished Professor, an endowed professorship established by Chester Fritz.[4][5] She has received several awards for her work, including an Ellison Medical Foundation Senior Scholar Award and the Glenn Award for Research in Biological Mechanisms of Aging. Her contributions to the field of the biology of aging were recognized in 2013 by receipt of the Denham Harman Lifetime Achievement Research Award from the American Aging Association, the society's highest honor.

Brown-Borg is a leader in the field of aging. In 2010 served as president of the American Aging Association; she also has served as Chair of Biological Sciences section of Gerontological Society of America. Her contribution to aging and these societies have been recognized by her election as a Fellow of the Gerontological Society of America in 2006 and a Fellow of the American Aging Association in 2016.

In postdoctoral research completed by Brown-Borg in Andrzej Bartke's laboratory, Brown-Borg demonstrated that the Ames Dwarf mouse had a significant increase in lifespan.[6][7] Brown-Borg's work has also linked growth hormone signaling to oxidative stress and methionine metabolism,[8][9][10] and highlighted the role of growth hormone in the pro-longevity effects of methionine restriction.[11]

Honors and awards

Professional societies

References
  1. Dakota, - The University of North. "Holly Brown-Borg, Ph.D. | Faculty Staff | Archive | Biomedical Sciences | School of Medicine & Health Sciences | UND: University of North Dakota". www.med.und.edu. Retrieved 2017-08-24.
  2. "Lifeboat Foundation Bios: Professor Holly M. Brown-Borg". lifeboat.com. Retrieved 2017-08-24.
  3. "Brown-Borg, Holly | PhD – #OW2017 | ObesityWeek 2017". obesityweek.com. Retrieved 2017-08-24.
  4. Dakota, - The University of North. "Chester Fritz Distinguished Professors | Provost | UND: University of North Dakota". und.edu. Retrieved 2017-08-24.
  5. Dakota, - The University of North. "Holly Brown-Borg | Faculty | UND: University of North Dakota". und.edu. Retrieved 2017-08-24.
  6. Stipp, David (2010-07-08). The Youth Pill: Scientists at the Brink of an Anti-Aging Revolution. Penguin. ISBN 9781101442289.
  7. Brown-Borg, H. M.; Borg, K. E.; Meliska, C. J.; Bartke, A. (1996-11-07). "Dwarf mice and the ageing process". Nature. 384 (6604): 33. Bibcode:1996Natur.384...33B. doi:10.1038/384033a0. ISSN 0028-0836. PMID 8900272. S2CID 4327014.
  8. Brown-Borg, Holly M.; Rakoczy, Sharlene G.; Wonderlich, Joseph A.; Rojanathammanee, Lalida; Kopchick, John J.; Armstrong, Vanessa; Raasakka, Debbie (December 2014). "Growth hormone signaling is necessary for lifespan extension by dietary methionine". Aging Cell. 13 (6): 1019–1027. doi:10.1111/acel.12269. ISSN 1474-9726. PMC 4244257. PMID 25234161.
  9. Brown-Borg, Holly M.; Rakoczy, Sharlene G.; Uthus, Eric O. (March 2005). "Growth hormone alters methionine and glutathione metabolism in Ames dwarf mice". Mechanisms of Ageing and Development. 126 (3): 389–398. doi:10.1016/j.mad.2004.09.005. ISSN 0047-6374. PMID 15664625. S2CID 25155125.
  10. Brown-Borg, Holly M.; Rakoczy, Sharlene G. (December 2003). "Growth hormone administration to long-living dwarf mice alters multiple components of the antioxidative defense system". Mechanisms of Ageing and Development. 124 (10–12): 1013–1024. doi:10.1016/j.mad.2003.07.001. ISSN 0047-6374. PMID 14659590. S2CID 22539005.
  11. "Growth Hormone Guidance". The Scientist. Retrieved 2017-08-24.
  12. "American Aging Association - Fellows". www.americanagingassociation.org. Retrieved 2017-11-18.
  13. Dakota, - The University of North. "UND researcher Holly Brown-Borg honored with Lifetime Achievement Award | 06 | 2013 | News | School of Medicine & Health Sciences | UND: University of North Dakota". www.med.und.edu. Retrieved 2017-08-24.
  14. "HIGHER EDUCATION NOTES: UND committee for new med school". Retrieved 2017-11-18.
  15. "2014 Scientific Committees". AFAR. Retrieved 2017-08-24.
  16. "2103 Scientific Committees". AFAR. Retrieved 2017-08-24.
  17. "2011 Scientific Committees". AFAR. Retrieved 2017-08-24.
  18. "Glenn Foundation for Medical Research Glenn Award for Research in Biological Mechanisms of Aging". glennfoundation.org. Retrieved 2017-11-18.
  19. "American Aging Association - Organization". www.americanagingassociation.org. Retrieved 2017-11-18.
  20. "Gerontology News" (PDF). The Gerontological Society of America. July 2009. Retrieved November 18, 2017.
  21. "'Manna from Heaven': Holly Brown-Borg Receives an Unsolicited Award to Support Research on Aging in Ames Dwarf Mice". www.newswise.com. Retrieved 2017-08-24.
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