Horse ointment

Horse ointment, known as horse oil and horse fat, is a topical formulation derived from subcutaneous fat of horses.[1] With its thick and highly viscous properties, horse ointment is intended for topical use on human skin and mucous membranes to provide moisturization and boost the restoration of damaged skin. Horse ointment preparations was traditionally used in ancient China for the treatment of qi deficiency,[2] haemorrhoids, burns and xeroderma.[3] Due to a high proportion of fatty acids in horse ointment, which are similar to human skin fat, it can effectively penetrate through the skin surface. Nowadays, it is commonly applied to skin for the purpose of soothing redness and irritation. It is considered a natural skincare product with low risks of sensitization and irritation and is safe for people of all ages, including infants and seniors.

Use of horse ointment in ancient Chinese medicine

Horse ointment is a valuable preparation for the treatment of various skin conditions. Horse ointment originated in China and has a history of more than 4,000 years. Its usage was recorded in many ancient Chinese medical books. Lingshu jing was the first pharmacopoeia that included information about the highly moisturising properties and effectiveness in the treatment of milia of horse ointment. Li Shizhen, a well-known Chinese physician and writer of Compendium of Materia Medica, mentioned the use of horse ointment in the treatment of dyschromia, eczema, and burns. The famous doctor Tao Hongjing also mentioned in Compendium of Materia Medica that horse oil can help to promote hair growth.

Ingredients and their functions

The following table summarises the major ingredients commonly found in horse ointment formulations, their effects on the skin, as well as the safety score determined by the US Environmental Working Group (EWG).[4] Horse oil cream of different brands may have slight variations in their formulations. The table below only indicates the major ingredients commonly found in horse oil cream formulations.

Ingredient safety points are quoted from the EWG US Environmental Working Group. They are used to indicate the potential risks of long-term use of the ingredient to human skin and health. Ingredient safety points range from 1-10, with 10 representing the highest risk and 1 representing the lowest risk.

Ingredients Role Ingredient safety points Based on EWG

(0-10)

Water Solvent 1
Cetyl Alcohol Emulsion stabiliser, moisturizer, thickener 1
Glycerin Moisturiser 2
Alpha-Lipoic Acid (ALA) Antioxidant 1
Oleic acid Moisture barrier 1
Coenzyme Q10 Skin cells replenisher unknown
Hyalurnic acid Skin conditioner unknown
Palmitic acid Emollient 1
Collagen Moisturiser and for regenerating and firming skin 1
Vitamin E Antioxidant 1-2
Glycyrrhetinic acid For calming skin and minimising irritation 4
Liquid paraffin Emollient 1
Polysorbate 80 Emlusifier 1-3
Horse Fat Skin conditioning unknown
Sodium ascorbyl phosphate Antioxidant 1
Urea Moisturiser 1-3
Dimethicone Emollient 1
Rosemary leaf extract Moisturiser 1
Phenoxyethanol Fragrance, Preservative 4
Disodium/Trisodium EDTA Chelating agent 1

Overall, the safety points of ingredients commonly found in horse ointment formulations ranges between 1-4, indicating a low risk of causing skin or other health issues. Although horse ointment itself is a nature skin moisturiser, different ingredients might be added in the production process to mask the special odour of horse oil as well as to add nutrients that can attenuate the skin replenishing effect of horse ointment.

Production

The extraction of horse oil is a complex process that requires the use of large-scale machines. Horse fatty tissues are first ground with a meat grinder and then mixed with water. Rendering horse oil adopts a step-wise approach. Horse fat is first extracted in a vacuum system at a temperature between 60–110 °C. Rendered horse oil is then collected, filtered, and neutralized with 0.2% sodium hydroxide. It is then transferred to a stainless steel container in a water bath at 100 °C for 30 minutes for the precipitation of impurities.[5] Modern manufacturing of horse ointment usually involves purification to remove the unique odour of horse oil, which enables it to be a useful cosmetic product widely used nowadays.[6]

Composition and chemistry

A typical high-purity grade of horse ointment is composed predominantly of unsaturated acids. Compared to saturated acids, unsaturated acids are more suitable for skin applications. Two major substances in horse ointments make it a good remedy for skin conditions, namely alphalinolenic acid and linoleic acid. Alphalinolenic acid is an essential omega-3 fatty acid that exerts anti-inflammatory effects, while linolenic acid is an omega-6 fatty acid that moisturizes the skin to prevent dryness and reduces inflammatory mediators.[7] In addition to its skin repairment property, a recent study discovered that horse ointments could also provide a protective effect against oxidative stress. Experimental results showed that horse ointments absorb UVB radiation and remove reactive oxygen species, thus protecting human HaCaT keratinocytes from UVB-induced oxidative stress and preventing cell structural damage, skin necrosis, and aging.[8]

Cosmetic use

Preventing acne and fading scars

Horse ointment is rich in vitamin F, which exerts a natural anti-inflammatory effect and prevents flare-ups of acne. It can also boost the repairment of damaged skin cells and speed up the fading of scars.[9]

Reducing pore size

Some horse ointment formulations contain natural moisturisers extracted from plants, such as rosemary, horsetail, hops, pine, and lemon. These natural moisturizers have a strong skin repair abilities, which is essential in boosting skin metabolism, maintaining skin health, as well as reducing pore size.

Long-lasting hydration of skin

Horse ointment contains coenzyme Q10, hyaluronic acid, and collagen that can maintain the natural moisture barrier of the skin to prevent water loss from the skin. High oleic acid content in horse oil disturbs the natural lipid bilayer of the cuticle and allows effective penetration into the skin. Besides, it also contains deep sea shark essence which allows deep penetration into the skin.[10]

Anti-aging (reduce formation of spots and wrinkles)

Horse oil contains sophorolipids and natural ingredients such as horsetail, pine hops, which promotes the synthesis of collagen in the skin and thus maintains elasticity and prevents wrinkle formation.[11]

Promote hair growth

Liposomes in horse oil stimulate hair follicles to enter the anagen phase of the hair growth cycle, thus shortening the time for hair growth.[12]

Other uses

Burns

It has been shown in researches that horse oil has an anti-inflammatory effect that can treat skin burns. By absorbing UVB radiation and eliminating reactive oxygen species, horse oil protects human HaCaT keratinocytes from UVB-induced oxidative stress, reducing structural damage and death of cells. In addition to that, horse oil is rich in vitamin E and linolenic acid. After these substances are well absorbed and utilized by the skin, they can improve the cell activity of the skin. It can also enhance the resistance of the skin, which helps to prevent inflammation and other skin diseases, thus maintaining a healthy state of the skin.

Eczema

Horse ointment contains glycyrrhetinic acid, which is a medicinal ingredient obtained from the herb liquorice. In the treatment of atopic dermatitis, glycyrrhetinic acid has a similar effect to topical hydrocortisone. It was also suggested as an alternative for infants who show allergic reactions to the use of Vaseline.

Potential side effects

Although horse ointment is generally considered safe for topical use, it may still cause allergic reactions in some people. Symptoms of an allergic reaction may include rash, itching, swelling, and difficulty breathing. If you experience any of these symptoms after using horse ointment, stop using it immediately and consult a doctor. Additionally, horse ointment is not recommended for use on broken or irritated skin, as it may cause further irritation or infection. As with any new skincare product, it is recommended to perform a patch test on a small area of skin before applying it to larger areas of the body.

Studies on horse ointments

Horse oil is one of the most common natural moisturising ingredients in cosmetic products in Asian countries. It has been claimed to have antibacterial, anti-inflammatory, and antipruritic effects on the skin. However, most studies related to the efficacy of horse oil are written in Japanese or Korean without any English translations, thus making it difficult for dermatologists to analyze and discuss the findings.[13]

Ethical concerns

Horse oil is extracted from a mixture of fat from the manes, tail root, and abdomens of horses in alpine regions, which raises ethical concerns. Some vegetarians and animal-rights activists hold firm to their belief that using horse for the production of horse ointment is extremely cruel and unsustainable.

Market value

After refining, horse oil is a high-quality raw material for the production of high-end cosmetics, with a huge market potential. The development and production of horse oil ointment and other associated cosmetic products have extended the chain of horse product development, increasing the output value year by year. Horse ointment is now widely produced mainly in the Kyushu area.

References

  1. Yu, Jiuwang; Wang, Lu; Ding, Jiang; Wu, Lan (2021-12-01). "Extraction of Oleic Acid from Animals Oil and Its Anti-inflammatory Effect on Network Pharmacology". Iranian Journal of Science and Technology, Transactions A: Science. 45 (6): 1905–1913. doi:10.1007/s40995-021-01168-3. ISSN 2364-1819. S2CID 238709404.
  2. "Journal of Beijing University of Traditional Chinese Medicine", No. 2, 1994 | Chen Wenwei".
  3. Qiburi, Qiburi; Ganbold, Tsogzolmaa; Bao, Qingming; Da, Man; Aoqier, Aoqier; Temuqile, Temuqile; Baigude, Huricha (2020-01-10). "Bioactive components of ethnomedicine Eerdun Wurile regulate the transcription of pro-inflammatory cytokines in microglia". Journal of Ethnopharmacology. 246: 112241. doi:10.1016/j.jep.2019.112241. ISSN 0378-8741. PMID 31533078. S2CID 202686727.
  4. "EWG Skin Deep® Cosmetics Database". EWG. Retrieved 2023-04-03.
  5. Cho, Man Jae; Kim, Hyun Jung (2020-02-01). "Effects of rendering and α-tocopherol addition on the oxidative stability of horse fat". Food Science and Biotechnology. 29 (2): 169–177. doi:10.1007/s10068-019-00653-1. ISSN 2092-6456. PMC 6992833. PMID 32064125.
  6. KR 101529864, Lee, Chung-Woo, "Method for purifying horse oil", published 2015-06-19
  7. "Efficacy of horse oil on lipopolysaccharide-induced inflammation in human keratinocytes".
  8. Piao, Mei; Kang, Kyoung; Zhen, Ao; Kang, Hee; Koh, Young; Kim, Bong; Hyun, Jin (2019). "Horse Oil Mitigates Oxidative Damage to Human HaCaT Keratinocytes Caused by Ultraviolet B Irradiation". International Journal of Molecular Sciences. 20 (6): 1490. doi:10.3390/ijms20061490. PMID 30934595.
  9. Goik, Urszula; Goik, Tomasz; Załęska, Izabela (April 2019). "The Properties and Application of Argan Oil in Cosmetology". European Journal of Lipid Science and Technology. 121 (4): 1800313. doi:10.1002/ejlt.201800313. ISSN 1438-7697. S2CID 104351204.
  10. Yu, Jiuwang; Wang, Lu; Ding, Jiang; Wu, Lan (2021-12-01). "Extraction of Oleic Acid from Animals Oil and Its Anti-inflammatory Effect on Network Pharmacology". Iranian Journal of Science and Technology, Transactions A: Science. 45 (6): 1905–1913. doi:10.1007/s40995-021-01168-3. ISSN 2364-1819. S2CID 238709404.
  11. Maeng, Yoojae; Kim, Kyoung Tae; Zhou, Xuan; Jin, Litai; Kim, Ki Soo; Kim, Young Heui; Lee, Suyeon; Park, Ji Ho; Chen, Xiuyu; Kong, Mingxia; Cai, Lu; Li, Xiaokun (September 2018). "A novel microbial technique for producing high-quality sophorolipids from horse oil suitable for cosmetic applications". Microbial Biotechnology. 11 (5): 917–929. doi:10.1111/1751-7915.13297. PMC 6116743. PMID 30022625.
  12. "The effect of liposomed horse oil on the hair growth in C57BL/6 mic". ResearchGate.
  13. Hon, K. L.; Kung, J. S.; Ng, W. G.; Leung, T. F. (2018). "Emollient treatment of atopic dermatitis: latest evidence and clinical considerations". Drugs in Context. 7: 212530. doi:10.7573/dic.212530. PMC 5908267. PMID 29692852.
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