Hybrid oncocytoma/chromophobe renal cell carcinoma

Hybrid oncocytoma/chromophobe renal cell carcinoma is rare subtype of renal cell carcinoma.[1] It arises from intercalated cells of cortical collecting ducts of the kidney. It is associated with extreme hypodiploidy with multiple losses of entire chromosomes 1, 2, 6, 10, 13, 17, 21 and Y.

Hybrid oncocytoma/chromophobe renal cell carcinoma
SpecialtyOncology/Nephrology

References

  1. Ruiz-Cordero, Roberto; Rao, Priya; Li, Lerong; Qi, Yuan; Atherton, Daniel; Peng, Bo; Singh, Rajesh R.; Kim, Tae-Beom; Kawakami, Fumi; Routbort, Mark J.; Alouch, Nail; Chow, Chi-Wan B.; Tang, Ximing; Lu, Wei; Brimo, Fadi; Matin, Surena F.; Wood, Christopher G.; Tannir, Nizar M.; Wistuba, Ignacio I.; Chen, Ken; Wang, Jing; Medeiros, L. Jeffrey; Karam, Jose A.; Tamboli, Pheroze; Sircar, Kanishka (November 2019). "Hybrid oncocytic/chromophobe renal tumors are molecularly distinct from oncocytoma and chromophobe renal cell carcinoma". Modern Pathology. 32 (11): 1698–1707. doi:10.1038/s41379-019-0304-y. ISSN 1530-0285.
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