IFT74

Intraflagellar transport protein 74 homolog (IFT74), also known as coiled-coil domain-containing protein 2 (CCDC2) and capillary morphogenesis gene 1 protein (CMG1), is a protein that in humans is encoded by the IFT74 gene.[5][6]

IFT74
Identifiers
AliasesIFT74, CCDC2, CMG-1, CMG1, intraflagellar transport 74, BBS20, BBS22, SPGF58, JBTS40
External IDsOMIM: 608040 MGI: 1914944 HomoloGene: 11831 GeneCards: IFT74
Orthologs
SpeciesHumanMouse
Entrez

80173

67694

Ensembl

ENSG00000096872

ENSMUSG00000028576

UniProt

Q96LB3

Q8BKE9

RefSeq (mRNA)

NM_001099222
NM_001099223
NM_001099224
NM_025103
NM_001349928

NM_001290568
NM_026319

RefSeq (protein)

NP_001092692
NP_001092693
NP_001092694
NP_079379
NP_001336857

NP_001277497
NP_080595

Location (UCSC)Chr 9: 26.95 – 27.07 MbChr 4: 94.61 – 94.69 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

BCMG1 is upregulated by umbilical vein endothelial cells during capillary morphogenesis.[6]

References

  1. GRCh38: Ensembl release 89: ENSG00000096872 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000028576 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: intraflagellar transport 74 homolog (Chlamydomonas)".
  6. Bell SE, Mavila A, Salazar R, Bayless KJ, Kanagala S, Maxwell SA, Davis GE (August 2001). "Differential gene expression during capillary morphogenesis in 3D collagen matrices: regulated expression of genes involved in basement membrane matrix assembly, cell cycle progression, cellular differentiation and G-protein signaling". J. Cell Sci. 114 (Pt 15): 2755–73. doi:10.1242/jcs.114.15.2755. PMID 11683410.

Further reading


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