IK (gene)

Protein Red is a protein that in humans is encoded by the IK gene.[5][6]

IK
Identifiers
AliasesIK, CSA2, RED, IK cytokine, down-regulator of HLA II, RER, IK cytokine
External IDsOMIM: 600549 MGI: 1345142 HomoloGene: 36193 GeneCards: IK
Orthologs
SpeciesHumanMouse
Entrez

3550

24010

Ensembl

ENSG00000113141

ENSMUSG00000024474

UniProt

Q13123
Q95HA6

Q9Z1M8

RefSeq (mRNA)

NM_006083

NM_011879

RefSeq (protein)

NP_006074
NP_006074.2

NP_036009

Location (UCSC)Chr 5: 140.65 – 140.66 MbChr 18: 36.88 – 36.89 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

The protein encoded by this gene was identified by its RED repeat, a stretch of repeated arginine, glutamic acid and aspartic acid residues. The protein localizes to discrete dots within the nucleus, excluding the nucleolus. Its function is unknown. This gene maps to chromosome 5; however, a pseudogene may exist on chromosome 2.[6]

References

  1. GRCh38: Ensembl release 89: ENSG00000113141 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000024474 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Krief P, Augery-Bourget Y, Plaisance S, Merck MF, Assier E, Tanchou V, Billard M, Boucheix C, Jasmin C, Azzarone B (Dec 1994). "A new cytokine (IK) down-regulating HLA class II: monoclonal antibodies, cloning and chromosome localization". Oncogene. 9 (12): 3449–56. PMID 7970704.
  6. "Entrez Gene: IK IK cytokine, down-regulator of HLA II".

Further reading


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