IMP3

U3 small nucleolar ribonucleoprotein protein IMP3 is a protein that in humans is encoded by the IMP3 gene.[5][6][7]

IMP3
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesIMP3, BRMS2, C15orf12, MRPS4, U3 small nucleolar ribonucleoprotein, IMP U3 small nucleolar ribonucleoprotein 3
External IDsOMIM: 612980 MGI: 1916119 HomoloGene: 6120 GeneCards: IMP3
Orthologs
SpeciesHumanMouse
Entrez

55272

102462

Ensembl

ENSG00000177971

ENSMUSG00000032288

UniProt

Q9NV31

Q921Y2

RefSeq (mRNA)

NM_018285

NM_133976

RefSeq (protein)

NP_060755

NP_598737

Location (UCSC)Chr 15: 75.64 – 75.65 MbChr 9: 56.84 – 56.85 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

This gene encodes the human homolog of the yeast Imp3 protein. The protein localizes to the nucleoli and interacts with the U3 snoRNP complex. The protein contains an S4 domain.[7]

References

  1. GRCh38: Ensembl release 89: ENSG00000177971 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000032288 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Kenmochi N, Suzuki T, Uechi T, Magoori M, Kuniba M, Higa S, Watanabe K, Tanaka T (September 2001). "The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders". Genomics. 77 (1–2): 65–70. doi:10.1006/geno.2001.6622. PMID 11543634.
  6. Granneman S, Gallagher JE, Vogelzangs J, Horstman W, van Venrooij WJ, Baserga SJ, Pruijn GJ (April 2003). "The human Imp3 and Imp4 proteins form a ternary complex with hMpp10, which only interacts with the U3 snoRNA in 60-80S ribonucleoprotein complexes". Nucleic Acids Research. 31 (7): 1877–87. doi:10.1093/nar/gkg300. PMC 152815. PMID 12655004.
  7. "Entrez Gene: IMP3 IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)".

Further reading

Sources


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