INO80B (gene)
INO80 complex subunit B is a protein that in humans is encoded by the INO80B gene. [5]
INO80 stabilizes replication forks and counteracts mislocalization of H2A.Z
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| Aliases | INO80B, HMGA1L4, HMGIYL4, IES2, PAP-1BP, PAPA-1, ZNHIT4, hIes2, PAPA1, INO80 complex subunit B | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 616456 MGI: 1917270 HomoloGene: 32566 GeneCards: INO80B | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Function
This gene encodes a subunit of an ATP-dependent chromatin remodeling complex, INO80, which plays a role in DNA and nucleosome-activated ATPase activity and ATP-dependent nucleosome sliding. Readthrough transcription of this gene into the neighboring downstream gene, which encodes WW domain-binding protein 1, generates a non-coding transcript.
References
- GRCh38: Ensembl release 89: ENSG00000115274 - Ensembl, May 2017
- GRCm38: Ensembl release 89: ENSMUSG00000030034 - Ensembl, May 2017
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Entrez Gene: INO80 complex subunit B". Retrieved 2016-12-13.
Further reading
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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