Insulin like 6

Insulin like 6 is a protein that in humans is encoded by the INSL6 gene. [5]

INSL6
Identifiers
AliasesINSL6, RIF1, insulin like 6
External IDsOMIM: 606414 MGI: 1351595 HomoloGene: 5197 GeneCards: INSL6
Orthologs
SpeciesHumanMouse
Entrez

11172

27356

Ensembl

ENSG00000120210

ENSMUSG00000050957

UniProt

Q9Y581

Q9QY05

RefSeq (mRNA)

NM_007179

NM_013754

RefSeq (protein)

NP_009110

NP_038782

Location (UCSC)Chr 9: 5.12 – 5.19 MbChr 19: 29.3 – 29.3 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

The protein encoded by this gene contains a classical signature of the insulin superfamily and is significantly similar to relaxin and relaxin-like factor. This gene is preferentially expressed in testis. Its expression in testis is restricted to interstitial cells surrounding seminiferous tubules, which suggests a role in sperm development and fertilization.

References

  1. GRCh38: Ensembl release 89: ENSG00000120210 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000050957 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Insulin like 6". Retrieved 2016-02-25.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.