ITGB3BP

Centromere protein R is a protein that in humans is encoded by the ITGB3BP gene.[5][6][7]

ITGB3BP
Identifiers
AliasesITGB3BP, CENP-R, CENPR, HSU37139, NRIF3, TAP20, integrin subunit beta 3 binding protein
External IDsOMIM: 605494 MGI: 1914983 HomoloGene: 8617 GeneCards: ITGB3BP
Orthologs
SpeciesHumanMouse
Entrez

23421

67733

Ensembl

ENSG00000142856

ENSMUSG00000028549

UniProt

Q13352

Q9CQ82

RefSeq (mRNA)

NM_001206739
NM_014288
NM_001347145
NM_001347147
NM_001347148

NM_026348
NM_001362974
NM_001362975
NM_001362976

RefSeq (protein)

NP_001193668
NP_001334074
NP_001334076
NP_001334077
NP_055103

NP_080624
NP_001349903
NP_001349904
NP_001349905

Location (UCSC)Chr 1: 63.44 – 63.59 MbChr 4: 99.65 – 99.79 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

ITGB3BP has been shown to interact with:

References

  1. GRCh38: Ensembl release 89: ENSG00000142856 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000028549 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Shattil SJ, O'Toole T, Eigenthaler M, Thon V, Williams M, Babior BM, Ginsberg MH (December 1995). "Beta 3-endonexin, a novel polypeptide that interacts specifically with the cytoplasmic tail of the integrin beta 3 subunit". J Cell Biol. 131 (3): 807–16. doi:10.1083/jcb.131.3.807. PMC 2120613. PMID 7593198.
  6. Li D, Desai-Yajnik V, Lo E, Schapira M, Abagyan R, Samuels HH (February 2000). "NRIF3 is a novel coactivator mediating functional specificity of nuclear hormone receptors". Mol Cell Biol. 19 (10): 7191–202. doi:10.1128/mcb.19.10.7191. PMC 84712. PMID 10490654.
  7. "Entrez Gene: ITGB3BP integrin beta 3 binding protein (beta3-endonexin)".
  8. Fujimoto TT, Katsutani S, Shimomura T, Fujimura K (January 2002). "Novel alternatively spliced form of beta(3)-endonexin". Thromb. Res. 105 (1): 63–70. doi:10.1016/s0049-3848(01)00405-4. PMID 11864709.
  9. Ohtoshi A, Maeda T, Higashi H, Ashizawa S, Yamada M, Hatakeyama M (January 2000). "beta3-endonexin as a novel inhibitor of cyclin A-associated kinase". Biochem. Biophys. Res. Commun. 267 (3): 947–52. doi:10.1006/bbrc.1999.2007. PMID 10673397.
  10. Besta F, Massberg S, Brand K, Müller E, Page S, Grüner S, Lorenz M, Sadoul K, Kolanus W, Lengyel E, Gawaz M (October 2002). "Role of beta(3)-endonexin in the regulation of NF-kappaB-dependent expression of urokinase-type plasminogen activator receptor". J. Cell Sci. 115 (Pt 20): 3879–88. doi:10.1242/jcs.00081. PMID 12244126.
  11. Li D, Wang F, Samuels HH (December 2001). "Domain structure of the NRIF3 family of coregulators suggests potential dual roles in transcriptional regulation". Mol. Cell. Biol. 21 (24): 8371–84. doi:10.1128/MCB.21.24.8371-8384.2001. PMC 100002. PMID 11713274.

Further reading


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