Band cell

A band cell (also called band neutrophil, band form or stab cell) is a cell undergoing granulopoiesis, derived from a metamyelocyte, and leading to a mature granulocyte.

Band cell
Details
Precursormetamyelocyte
Gives rise toGranulocyte
Identifiers
THH2.00.04.3.04011
FMA86471
Anatomical terms of microanatomy
Neutrophilic band cell
Basophilic band cell
Eosinophilic band cell

It is characterized by having a curved but not lobular nucleus.[1]

The term "band cell" implies a granulocytic lineage (e.g., neutrophils).[2]

Clinical significance

Band neutrophils are an intermediary step prior to the complete maturation of segmented neutrophils. Polymorphonuclear neutrophils are initially released from the bone marrow as band cells, as the immature neutrophils become activated or exposed to pathogens, their nucleus will take on a segmented appearance. An increase in the number of these immature neutrophils in circulation can be indicative of a infection for which they are being called to fight against, or some inflammatory process. The increase of band cells in the circulation is called bandemia and is a "left shift" process.

Blood reference ranges for neutrophilic band cells in adults are 3 to 5% of white blood cells,[3] or up to 0.7 x109/L.[4]

An excess may sometimes be referred to as bandemia.

See also

Additional images
  • Band neutrophil in peripheral blood film
    Band neutrophil in peripheral blood film
  • Hematopoiesis
    Hematopoiesis

References
  1. "band cell" at Dorland's Medical Dictionary
  2. "Eosinophilic band". Archived from the original on 2008-08-29. Retrieved 2009-03-01.
  3. Last page of Deepak A. Rao; Le, Tao; Bhushan, Vikas (2007). First Aid for the USMLE Step 1 2008 (First Aid for the Usmle Step 1). McGraw-Hill Medical. ISBN 978-0-07-149868-5.
  4. Clinical Laboratory Medicine. By Kenneth D. McClatchey. Page 807.


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