Adipiodone

Adipiodone (INN, or iodipamide; trade names Cholografin and Biligrafin) is a pharmaceutical drug used as a radiocontrast agent in X-ray imaging. It was introduced in the 1950s.[1][2]

Adipiodone
Clinical data
Trade namesCholografin, Biligrafin
Other names3-[[6-[(3-Carboxy-2,4,6-triiodophenyl)amino]-6-oxohexanoyl]amino]-2,4,6-triiodobenzoic acid
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
  • 3-{5-[(3-carboxy-2,4,6-triiodophenyl)carbamoyl]pentanamido}-2,4,6-triiodobenzoic acid
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.009.187
Chemical and physical data
FormulaC20H14I6N2O6
Molar mass1139.767 g·mol−1
3D model (JSmol)
  • O=C(Nc1c(I)c(c(I)cc1I)C(=O)O)CCCCC(=O)Nc2c(I)c(C(=O)O)c(I)cc2I
  • InChI=1S/C20H14I6N2O6/c21-7-5-9(23)17(15(25)13(7)19(31)32)27-11(29)3-1-2-4-12(30)28-18-10(24)6-8(22)14(16(18)26)20(33)34/h5-6H,1-4H2,(H,27,29)(H,28,30)(H,31,32)(H,33,34) checkY
  • Key:FFINMCNLQNTKLU-UHFFFAOYSA-N checkY
  (verify)

References

  1. Hastings-James R, Glazebrook AJ (April 1955). "Cholografin". Canadian Medical Association Journal. 72 (8): 561–5. PMC 1825662. PMID 14364399.
  2. Dilger SK, Nelson N, Venkatesh SK, Ehman EC, Fidler JL, Fletcher JG, et al. (September 2019). "Computed Tomography Cholangiography Using the Magnetic Resonance Contrast Agent Gadoxetate Disodium: A Phantom Study". Investigative Radiology. 54 (9): 572–579. doi:10.1097/RLI.0000000000000580. PMID 31261292. S2CID 195772743.
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