Isonicotinic acid

Isonicotinic acid or pyridine-4-carboxylic acid is an organic compound with the formula C5H4N(CO2H). It is a derivative of pyridine with a carboxylic acid substituent at the 4-position. It is an isomer of picolinic acid and nicotinic acid, which have the carboxyl group at the 2- and 3-position respectively compared to the 4-position for isonicotinic acid.

Isonicotinic acid[1]
Skeletal formula
Skeletal formula
Ball-and-stick model
Ball-and-stick model
Names
Preferred IUPAC name
Pyridine-4-carboxylic acid
Other names
Isonicotinic acid
4-Pyridinecarboxylic acid
p-Pyridinecarboxylic acid
4-Picolinic acid
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.000.208
KEGG
UNII
  • InChI=1S/C6H5NO2/c8-6(9)5-1-3-7-4-2-5/h1-4H,(H,8,9) checkY
    Key: TWBYWOBDOCUKOW-UHFFFAOYSA-N checkY
  • InChI=1/C6H5NO2/c8-6(9)5-1-3-7-4-2-5/h1-4H,(H,8,9)
    Key: TWBYWOBDOCUKOW-UHFFFAOYAV
  • c1cnccc1C(=O)O
Properties
C6H5NO2
Molar mass 123.111 g·mol−1
Appearance White to off-white crystalline solid
Density Solid
Melting point 310 °C (590 °F; 583 K) (sublimes)
Hazards
NFPA 704 (fire diamond)
NFPA 704 four-colored diamond
3
1
0
Safety data sheet (SDS) http://datasheets.scbt.com/sc-250188.pdf
Related compounds
Related compounds
 nicotinic acid, pyridine isoniazid
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Derivatives

Isonicotinic acids is a term loosely used for derivatives of isonicotinic acid. Hydrazide derivatives include isoniazid, iproniazid, and nialamide. Amide and ester derivatives include ethionamide and dexamethasone isonicotinate.

See also

References
  1. Isonicotinic acid at chemicalland21.com
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