Jaqueline Goés de Jesus

Jaqueline Góes de Jesus (born 1990) is a Brazilian scientist and researcher. She was part of the team which sequenced the Zika virus. During the COVID-19 pandemic, she was a member of the team responsible for sequencing the first genome of the SARS-CoV-2 virus in Brazil.

Not to be confused with Jaqueline Jesus.
Jaqueline Goés de Jesus
Jaqueline Goes in 2022
Alma mater
Scientific career
InstitutionsUniversity of São Paulo

Early life and education

Góes de Jesus is from Salvador in Northeast Brazil.[1][2] Her mother is a nursing technician and her father is a civil engineer.[2] She was a teenager when she decided to work in biomedical sciences. Her first research project involved investigations into HIV, which inspired her to pursue a career in global public health.[3] She studied biomedicine at the Escola Bahiana de Medicina e Saúde Pública.[4][5] Góes de Jesus moved to the Instituto Gonçalo Moniz for her graduate studies, earning a master's degree in biotechnology. Subsequently, Góes de Jesus completed a doctoral degree at the Federal University of Bahia, specialising in human and experimental pathology.[6] During her doctoral research she visited the University of Birmingham, where she was trained in nanopore sequencing.[5]

Research and career

After earning her doctoral degree Góes de Jesus joined the University of São Paulo Institute of Tropical Medicine as a São Paulo Research Foundation (FAPESP) research fellow. She started working on the ZIBRA (Zika in Brazil Real Time Analysis) project, which sought to understand the spread of zika virus in Brazil.[3][7] The ZIBRA project developed two mobile sequencing laboratories, with which they travelled Brazil aiming to sequence 750 genomes.[8]

Góes de Jesus subsequently used the ZIBRA mobile sequencing units to study the epidemiology of a dengue virus outbreak which occurred in Brazil.[9][10] The majority of infections occurred in São Paulo state, and Góes de Jesus focussed her study on two municipalities: (São José do Rio Preto and Araraquara). A large team of researchers identified that the strain of dengue virus during the 2019 outbreak was most similar to viruses found in Martinique and Guadeloupe.[11] Góes de Jesus is a member of the United Kingdom–Brazil Centre for Arbovirus Discovery, Diagnosis, Genomics and Epidemiology, Diagnosis, Genomics and Epidemiology (CADDE), an epidemics monitoring project that seeks to understand the circulation of arbovirus in Brazil and its persistence in non-epidemic periods.[12]

Alongside her academic work, Góes de Jesus is a science communicator, with a following of over 160,000 people on Instagram.[1][6]

COVID-19 pandemic

During the COVID-19 pandemic, Góes de Jesus worked with Ester Cerdeira Sabino to sequence the genome of SARS-CoV-2.[3][13] After receiving samples from the first infected Brazilian patient on February 26, the team sequenced the genome in 48 hours.[5][14] Their efforts made it possible to differentiate the version of SARS-CoV-2 that was infecting people in Brazil from the one that first emerged in Wuhan in January 2020.[15]

The team found that the version of SARS-CoV-2 which infected the first Brazilian patient was more akin to the late-January German strain than the original form, whereas the second form was closer to strains from the United Kingdom.[16] In March 2020 the team's success was recognised by Legislative Assembly of Bahia. Pastor Isidório Filho emphasised the importance of their work.[1][17] On March 6, Maurício de Sousa Produções turned Jesus into a character in the Turma da Mônica series.[18][19]

References
  1. "Os desafios da cientista negra que coordena a equipe de brasileiros que isolou o genoma do Coronavírus" [The challenges of the black scientist who coordinates the team of Brazilians who isolated the Coronavirus genome]. www.nsctotal.com.br (in Brazilian Portuguese). Retrieved 2020-05-29.
  2. "Conheça a cientista, negra e nordestina, que coordena a luta contra o Covid-19 no Brasil" [Meet the scientist, black and northeastern, who coordinates the fight against Covid-19 in Brazil]. Revista Marie Claire (in Brazilian Portuguese). Retrieved 2020-05-30.
  3. Andrion, Roseli (2020-03-06). "Dia da Mulher: Jaqueline Góes de Jesus, especialista em vírus" [Women's Day: Jaqueline Góes de Jesus, virus specialist]. Olhar Digital - O futuro passa primeiro aqui (in Brazilian Portuguese). Retrieved 2020-05-29.
  4. EPTV. "Cientista que mapeou o coronavírus estudou em Ribeirão Preto" [Scientist who mapped the coronavirus studied in Ribeirão Preto]. ACidade ON Ribeirão. Retrieved 2020-05-29.
  5. "Escola Bahiana de Medicina e Saúde Pública" [Bahiana School of Medicine and Public Health]. m.bahiana.edu.br. Archived from the original on 2020-08-11. Retrieved 2020-05-29.
  6. Leal, Bruno Leite / Mari. "Cientista que sequenciou genoma do coronavírus em apenas 48h é baiana" [Scientist who sequenced the coronavirus genome in just 48 hours is from Bahia]. www.bahianoticias.com.br (in Brazilian Portuguese). Retrieved 2020-05-30.
  7. "Who". www.zibraproject.org. Retrieved 2020-05-29.
  8. "About". www.zibraproject.org. Retrieved 2020-05-29.
  9. Faria, Nuno R.; da Costa, Antonio Charlys; Lourenço, José; Loureiro, Paula; Lopes, Maria Esther; Ribeiro, Roberto; Alencar, Cecilia Salete; Kraemer, Moritz U. G.; Villabona-Arenas, Christian J.; Wu, Chieh-Hsi; Thézé, Julien (2017-11-09). "Genomic and epidemiological characterisation of a dengue virus outbreak among blood donors in Brazil". Scientific Reports. 7 (1): 15216. doi:10.1038/s41598-017-15152-8. ISSN 2045-2322. PMC 5680240. PMID 29123142.
  10. Jesus, Jaqueline Goes de; Dutra, Karina Rocha; Salles, Flavia Cristina da Silva; Claro, Ingra Morales; Terzian, Ana Carolina; Candido, Darlan da Silva; Hill, Sarah C.; Thézé, Julien; D’Agostini, Tatiana Lang; Felix, Alvina Clara; Reis, Andreia F. Negri (2019-07-28). "Early identification of dengue virus lineage replacement in Brazil using portable genomic surveillance". bioRxiv: 716159. doi:10.1101/716159. S2CID 201205352.
  11. "Genomic Monitoring of Dengue Virus Serotype 2 in Brazil, 2019". Virological. 2019-07-09. Retrieved 2020-05-30.
  12. "UK-Brazil Joint Centre for Arbovirus Discovery, Diagnosis, Genomics and Epidemiology (CADDE)". UKRI. Retrieved 2020-05-29.
  13. Travae, Marques (2020-03-04). "Jaqueline Goes de Jesus was part of a large team of Brazilian scientists who sequenced the genome of the coronavirus in 48 hours; the new sequencing technologies used often allow academics to do this in even less time". Black Women Of Brazil. Retrieved 2020-05-30.
  14. "First cases of coronavirus disease (COVID-19) in Brazil, South America (2 genomes, 3rd March 2020)". Virological. 2020-02-28. Retrieved 2020-05-30.
  15. "Two complete genome sequence for coronavirus in Brazil were published". EurekAlert!. Retrieved 2020-05-29.
  16. Alvim - @marianaalvim, Mariana (2020-02-29). "Os bastidores e resultados da corrida de cientistas brasileiros para sequenciar coronavírus em tempo recorde" [Behind the scenes and results of the race of Brazilian scientists to sequence coronavirus in record time]. BBC News Brasil (in Portuguese). Retrieved 2020-05-29.
  17. Bahia, Alô Alô. "Baiana que sequenciou o genoma do Coronavírus deve ser homenageada pela ALBA" [Bahian who sequenced the Coronavirus genome should be honored by ALBA]. Alô Alô Bahia (in Brazilian Portuguese). Retrieved 2020-05-30.
  18. "Pesquisadoras do coronavírus 'viram' personagens de Mauricio de Sousa; veja" [Coronavirus researchers 'saw' characters from Mauricio de Sousa; Look]. noticias.uol.com.br (in Brazilian Portuguese). Retrieved 2020-05-30.
  19. Dia, O. (2020-03-07). "Turma da Mônica homenageia cientistas brasileiras que sequenciaram genoma do coronavírus" [Monica's Gang honors Brazilian scientists who sequenced the coronavirus genome]. O Dia - Brasil (in Brazilian Portuguese). Retrieved 2020-05-30.
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