Jenner Institute

The Jenner Institute is a research institute on the Old Road Campus in Headington, east Oxford, England. It was formed in November 2005 through a partnership between the University of Oxford and the UK Institute for Animal Health.[2] It is associated with the Nuffield Department of Medicine, in the Medical Sciences Division of Oxford University. The institute receives charitable support from the Jenner Vaccine Foundation.[3][4]

The Jenner Institute
Parent institutionUniversity of Oxford
EstablishedNovember 2005 (2005-11)
DirectorAdrian Hill
Staff100
Key peopleSarah Gilbert[1]
Helen McShane
Formerly calledEdward Jenner Institute for Vaccine Research
AddressOld Road Campus Research Building (ORCRB), Roosevelt Drive, Oxford OX3 7DQ, UK
Location
Old Road Campus Research Building
,
Oxford
,
United Kingdom
Coordinates51.7519293°N 1.2163045°W / 51.7519293; -1.2163045
Websitewww.jenner.ac.uk

The institute is led by Prof. Adrian Hill.[5] The institute develops vaccines and carries out clinical trials for diseases including malaria, tuberculosis (vaccine MVA85A), ebola, and MERS-Coronavirus.[6][7]

In 2020, the institute successfully developed the Oxford–AstraZeneca COVID-19 vaccine, in a project backed by private companies including Oxford Sciences Innovation, Google Ventures, and Sequoia Capital, among others.[8] When developed, the UK government backed trials, purchased 100 million does, and encouraged Oxford to work with AstraZeneca, a company based in Europe, instead of Merck & Co., a US-based company; while the US gave US$1.2bn of government funding in return for 300 million doses.[9][10] It collaborated with Italy's Advent Srl (part of the IRBM Group) on the development[11] and Germany's Merck Group on the manufacture of the COVID-19 vaccine.[3] Vaccinologist Dame Sarah Gilbert was one of the leading scientists involved in the development.[1][12]

The institute is named after the English physician and immunization pioneer Edward Jenner (1749–1823), who was a major contributor to the development of the smallpox vaccine.

History
The Jenner Institute Laboratories from the atrium of the Old Road Campus Research Building
Statue of Edward Jenner at the entrance of The Jenner Institute
Main article: Edward Jenner Institute for Vaccine Research

Previously, the Edward Jenner Institute for Vaccine Research was an independent research institute named after Edward Jenner, the inventor of vaccination. It was co-located with the Compton Laboratory of the Institute for Animal Health on a campus in the village of Compton in Berkshire. After occupying temporary laboratory space at the Institute for Animal Health from 1996, the institute moved to a newly completed laboratory building in 1998. Funding of the institute continued until October 2005, when it was relaunched replacing the four founding funding partners (GlaxoSmithKline, the Medical Research Council, the Biotechnology and Biological Sciences Research Council and the Department of Health) with the University of Oxford and the Institute for Animal Health.[13][14]

References
  1. Lane, Richard (2020). "Sarah Gilbert: carving a path towards a COVID-19 vaccine". The Lancet. 395 (10232): 1247. doi:10.1016/S0140-6736(20)30796-0. PMC 7162644. PMID 32305089.
  2. "The Jenner Institute". Health Check. UK: Nuffield Department of Medicine, University of Oxford. Archived from the original on 27 May 2020. Retrieved 17 April 2020.
  3. "Merck Supports Jenner Institute to Reach First Milestone in Covid-19 Vaccine Manufacturing" (Press release). Merck Group. Retrieved 17 April 2020.
  4. Jenner Institute on Twitter
  5. "Preparing for Future Epidemics". Health Check. UK: BBC. 10 June 2015. Retrieved 17 April 2020.
  6. "Ebola vaccine trial begins". BBC News. 17 September 2014.
  7. "Helen McShane". ndm.ox.ac.uk.
  8. "The Backstory: Vaccitech and its role in co-inventing the Oxford COVID-19 vaccine". Oxford Sciences Innovation. 23 November 2020. Archived from the original on 1 May 2021. Retrieved 25 March 2021.
  9. "The Oxford vaccine: the trials and tribulations of a world-saving jab". The Guardian. 26 June 2021. Archived from the original on 27 June 2021. Retrieved 27 June 2021.
  10. Keown C. "U.S. gives AstraZeneca $1.2 billion to fund Oxford University coronavirus vaccine — America would get 300 million doses beginning in October". MarketWatch. Archived from the original on 26 January 2021. Retrieved 30 March 2021.
  11. "The Jenner Institute signs an agreement with Advent to develop a novel coronavirus vaccine". IRBM. Archived from the original on 19 January 2021. Retrieved 18 April 2020.
  12. "Prof Sarah Gilbert: Coronavirus vaccine trials to start within days". The Andrew Marr Show. UK: BBC One. 19 April 2020. Retrieved 19 April 2020.
  13. "MRC Annual Report and Accounts 2005/06" (PDF). p. 11.
  14. "Annual report and financial statements for the year ended 31 March 2006".
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