John Diffley (biologist)

John Francis Xavier Diffley FRS FMedSci (born 4 March 1958) is an American biochemist and Associate Research Director at the Francis Crick Institute.[1] He is known for his contributions to the understanding of how DNA replication is initiated, and how it is subsequently regulated throughout the cell cycle and in response to DNA damage.[2]

John Diffley

FRS FMedSci
Born
John Francis Xavier Diffley

(1958-03-04) 4 March 1958
Alma materNew York University (BA, MSc, PhD)
Awards
Scientific career
FieldsChromatin replication, cell cycle, DNA damage checkpoints
Institutions

Research and career

Diffley was educated at New York University, obtaining his Ph.D. in 1985. He then worked as a postdoctoral researcher with Bruce Stillman at Cold Spring Harbor Laboratory. In 1990, he established his own research group at the Clare Hall Laboratories, Cancer Research UK, which is now part of the Francis Crick Institute. His group studies the mechanism and regulation of eukaryotic DNA replication.

Awards and honours

In 1998, Diffley was elected a member of European Molecular Biology Organisation (EMBO). He is also an elected member of Academia Europaea (2009) and the European Academy of Cancer Sciences (2011). He was elected a Fellow of the Royal Society (FRS)[3] in 2005, Fellow of the American Association for the Advancement of Science (AAAS) in 2007, and Fellow of the Academy of Medical Sciences (FMedSci) in 2011.

He is a recipient of the Paul Marks Prize for Cancer Research (2003), the Louis-Jeantet Prize for Medicine(2016)[4] and the Canada Gairdner International Award (2019).[5] He was elected to the National Academy of Sciences in 2020.

References
  1. "John Diffley". Francis Crick Institute. Retrieved 2019-10-24.
  2. "John DIFFLEY | Jeantet". October 2017.
  3. "John Diffley". Royal Society. Retrieved 2019-10-24.
  4. "John Diffley". Louis-Jeantet Foundation. October 2017. Retrieved 2019-10-24.
  5. "Canada Gairdner Awards 2019 Laureates". Gairdner Foundation. Retrieved 2019-10-24.


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