John Puskas

John D. Puskas is an American researcher, author, inventor and cardiovascular surgeon. As of 2022, he is Professor, Cardiovascular Surgery, Icahn School of Medicine at Mount Sinai,[1] and chairman, Department of Cardiovascular Surgery at Mount Sinai Morningside, Mount Sinai Beth Israel and Mount Sinai West. He holds 11 U.S. patents and co-founded the International Coronary Congress and the International Society for Coronary Artery Surgery.[2] He is credited by ResearchGate with 330 publications and 15,234 citations[3] and as of 2022 Scopus reports an h-index of 62.[4] Puskas is known for advancing coronary artery bypass (CABG) surgery by refining surgical techniques for all-arterial, off-pump CABG and inventing finer instruments to be used for advanced coronary bypass surgical procedures.[5] He is credited with performing the first totally thoracoscopic bilateral pulmonary vein isolation procedure.[6] He is the co-editor of State of the Art Surgical Coronary Revascularization,[7][8] the first textbook solely devoted to coronary artery surgery.[9]

John D. Puskas
CitizenshipUnited States
EducationPrinceton University

Harvard Medical School

Massachusetts General Hospital

Toronto General Hospital

Emory University
Occupation(s)Cardiovascular surgeon, researcher, educator
Medical career
ProfessionSurgeon
InstitutionsIcahn School of Medicine at Mount Sinai
ResearchRobotic and hybrid coronary bypass grafting, mitral valve repair, Atrial Fibrillation, novel artificial heart valves, arterial bypass grafting
Websitehttps://www.mountsinai.org/profiles/john-d-puskas

In 2021, Puskas ran the New York City Marathon with his patient who, in 2018, suffered cardiac arrest and was clinically dead for five minutes, but recovered after all-arterial CABG.[10] Their trainer, John Garlepp was another CABG patient of Puskas.[11]

Career

Life and education

Born in 1960, Puskas received his MD at Harvard Medical School in 1986 and in 1991, a Master of Science in Surgical Science (MSc) at the University of Toronto. Post-graduate training included a general surgery internship and residency, department of surgery, Massachusetts General Hospital; fellowship in cardiothoracic surgery at Emory University Hospitals, Atlanta, a lung transplantation research fellowship, division of thoracic surgery, Toronto General Hospital; and an advanced fellowship in tracheal surgery, Massachusetts General Hospital, Division of General Thoracic Surgery.[1][12][13]

Research

Puskas research concentrations include arterial bypass grafting, robotic and hybrid coronary bypass grafting, novel designs and materials for artificial heart valves, mitral and aortic valve repair and replacement, surgical and medical treatments for people with atrial fibrillation and surgical instruments for adult cardiac surgery.[14]

He founded the Emory University Cardiothoracic Clinical Research Unit in 2005 and was a founding investigator in the creation of the NIH Cardiothoracic Surgery Trials Network in 2007; he has served on the steering committee of that NIH Network since that time. As of 2022, he has served as the principal investigator (PI) of five multi-center FDA investigatory drug/device exemption trials in cardiovascular surgery. At Mount Sinai Health System, he founded and directs the Cardiovascular Clinical Research Unit at Mount Sinai Morningside and Mount Sinai Beth Israel Hospitals to create a multidisciplinary collaborative clinical research infrastructure allowing clinical cardiologists and surgeons to enroll patients in multiple trials. He led 47 clinical sites nationwide to conduct the first RCT of hybrid coronary revascularization.[15] He is listed on NIH RePORTER with 12 NHLBI PI roles.[16]

Clinical and practice

Puskas performs cardiovascular surgical procedures including all-arterial coronary bypass grafting, minimally invasive robotic coronary bypass surgery, hybrid coronary revascularization, off-pump coronary artery bypass surgery, ablation surgery for the treatment of atrial fibrillation, mitral valve repair/replacement, aortic valve replacement, valve-sparing aortic root replacement and surgery for aortic dissection.[17] He performed the first triple off-pump bypass surgery using minimally invasive coronary artery bypass graft instrumentation in 1997.[18] Between 1996 and 2022, he performed approximately 300 cardiac surgical cases annually, specializing in multiple arterial CABG and robotic CABG.[18] In 2019, Puskas, with Gianluca Torregrossa, MD, successfully performed two totally endoscopic coronary arterial bypass surgeries (TECABs) making Mount Sinai the only New York State health system qualified to make the procedure available.[19] As of 2022, Puskas has served as President of the International Society for Minimally Invasive Cardiothoracic Surgery (2009) and the International Society for Coronary Artery Surgery.

U.S. patents
Specifications
Patent No Title Licensed to
6,042,538 Device for Endoscopic Vessel Harvesting Medtronic
6,479,523 Pharmacological Drug Combination in Vagal-Induced Asystole Medtronic
6,429,217 Pharmacological Drug Combination in Vagal-Induced Asystole Medtronic
6,778,854 Methods of Indirectly Stimulating the Vagus nerve with an Electrical Field Medtronic
6,656,960 Methods of Performing Vagal-Induced Asystol Medtronic
7,072,720 Devices and Methods for Vagus Nerve Stimulation Medtronic
7,142,910 Methods of Indirectly Stimulating the Vagus Nerve with an Electrical Field Medtronic
7,310,552 Apparatus for Indirectly Stimulating the Vagus Nerve with an Electrical Field
7,340,299 Methods of Indirectly Stimulating the Vagus Nerve to Achieve Controlled Asystole
7,840,278 Devices and Methods for Vagus Nerve Stimulation
12/134,842 Dual Closing Guide for a Surgical Instrument Scanlan International, Inc.
14/030,606 Novel Sternal Retractor Scanlan International, Inc.

Present societies

*Present indicates 2022

Publications

Editorial

As of 2022, Puskas is a reviewer and editorial contributor to nine journals, including Annuals Thoracic Surgery, Journal of Thoracic and Cardiovascular Surgery, Heart Surgery Forum, The Lancet, The Journal of Cardiac Surgery, Circulation, Innovations, American College of Cardiology, European Association for Cardiothoracic Surgery.

Peer reviewed

PubMed lists 320 publications as of 2022.[20] A short list ranked by citations include:

Smith, P. K., Puskas, J. D., Ascheim, D. D., Voisine, P., Gelijns, A. C., Moskowitz, A. J., ... & Michler, R. E. (2014). Surgical treatment of moderate ischemic mitral regurgitation. New England Journal of Medicine, 371(23), 2178–2188; 273 citations[21]

Puskas, J. D., Thourani, V. H., Marshall, J. J., Dempsey, S. J., Steiner, M. A., Sammons, B. H., ... & Guyton, R. A. (2001). Clinical outcomes, angiographic patency, and resource utilization in 200 consecutive off-pump coronary bypass patients. The Annals of thoracic surgery, 71(5), 1477–1484; 324 citations[22]

Gaudino, M., Benedetto, U., Fremes, S., Biondi-Zoccai, G., Sedrakyan, A., Puskas, J. D., ... & Taggart, D. P. (2018). Radial-artery or saphenous-vein grafts in coronary-artery bypass surgery. New England Journal of Medicine, 378(22), 2069–2077; 295 citations[23]

Gillinov, A. M., Gelijns, A. C., Parides, M. K., DeRose Jr, J. J., Moskowitz, A. J., Voisine, P., ... & Argenziano, M. (2015). Surgical ablation of atrial fibrillation during mitral-valve surgery. New England Journal of Medicine, 372(15), 1399–1409; 261 citations[24]

El-Chami, M. F., Kilgo, P., Thourani, V., Lattouf, O. M., Delurgio, D. B., Guyton, R. A., ... & Puskas, J. D. (2010). New-onset atrial fibrillation predicts long-term mortality after coronary artery bypass graft. Journal of the American College of Cardiology, 55(13), 1370–1376; 338 citations[25]

Books and chapters

State of the Art Surgical Coronary Revascularization. ISBN 0198758782

Winston AD and Puskas JD. "Techniques for Multivessel OPCAB". Minimally Invasive Cardiac Surgery. 2ndEdition, edited by Oz MC and Goldstein DJ, Humana Press, 2003.[26]

Sharoni E and Puskas JD. "Techniques in Multivessel OPCAB". Operative Cardiac Surgery, edited by Gardner T J and Spray TL, Arnold Publishers, 2004.

Thourani VH and Puskas JD. "Coronary Artery Bypass Procedures·Medical Management of the Surgical Patient." Fourth Edition, edited by Lubin MF, Walker HK, Smith RB III, 2006.[27]

Song HK and Puskas JD. "Off-pump Coronary Artery Bypass Surgery". Mastery of Cardiothoracic Surgery, 2nd Edition, Lippincott Williams and Wilkins, New York, 2007.[28]

Richard J. Myung and John D. Puskas. "Off-Pump Coronary Artery Bypass Grafting for Repeat Coronary Revascularization", Redo Cardiac Surgery in Adults, 2nd Edition, Edited by Venkat R. Machiraju, Hartzell V. Schaff and Lars G. Svensson. Springer. 2011.[29]

Michael E. Halkos, John D. Puskas. "Minimally Invasive Coronary Artery Bypass Graft to Cardiac Surgery: Recent Advances and Techniques", 2012.[30]

Yanagawa B and Puskas JD. “Off-Pump Coronary Artery Bypass Grafting”, in Mastery of Techniques in Cardiac Surgery, 2016.

Michael E. Halkos, Emmanuel Moss, and John D. Puskas. “Chapter 2 Off-pump versus on-pump coronary artery bypass grafting”, in Core Concepts in Cardiac Surgery, Edited by David Taggart and Yasir Abu-Omar, Oxford University Press, 2018.

Bobby Yanagawa, Michael E. Halkos, John D. Puskas. “Chapter 21: Myocardial Revascularization Without Cardiopulmonary Bypass”, in Cardiac Surgery in the Adult, 5e, Edited by Lawrence H. Cohn, David H. Adams, Cenveo® Publisher Services, 2018.

See also
  • Mario Gaudino - cardiac surgeon and expert in coronary revascularization

References
  1. "John Puskas | CTSNet". www.ctsnet.org. Retrieved 2022-06-17.
  2. "India's first International Coronary Congress Inaugurated by Hon'ble President of India Shri Pranab Mukherjee - Core Sector Communique". Retrieved 2022-08-25.
  3. "ResearchGate". Retrieved 17 June 2022.
  4. "Scopus preview - Puskas, John Daniel - Author details - Scopus". www.scopus.com. Retrieved 2022-08-25.
  5. Myung, Richard J.; Halkos, Michael E.; Puskas, John D. (2010). "Less Invasive Approaches to Coronary Artery Bypass Grafting: Off-Pump Coronary Artery Bypass". Operative Techniques in Thoracic and Cardiovascular Surgery. 15 (3): 186–193. doi:10.1053/j.optechstcvs.2010.08.005. Retrieved 17 June 2022.
  6. "CCC Symposium". www.cccsymposiumlive.com. Retrieved 2022-06-17.
  7. Taggart, David P.; Puskas, John D. (2021). State of the Art Surgical Coronary Revascularization. Oxford University Press. ISBN 978-0-19-875878-5.
  8. State of the Art Surgical Coronary Revascularization. Oxford, New York: Oxford University Press. 2021-04-04. ISBN 978-0-19-875878-5.
  9. State of the Art Surgical Coronary Revascularization. Oxford University Press. 2020. doi:10.1093/med/9780198758785.001.0001/med-9780198758785 (inactive 1 August 2023). ISBN 978-0-19-181867-7.{{cite book}}: CS1 maint: DOI inactive as of August 2023 (link)
  10. Hambleton, Brittany (2021-11-07). "WATCH: Man running the NYC marathon with doctor who saved his life". Canadian Running Magazine. Retrieved 2022-08-25.
  11. "2021 TCS NYC Marathon: Man running the NYC Marathon with surgeon who saved him". ABC7 New York. 2021-11-07. Retrieved 2022-08-25.
  12. "Dr. John D. Puskas - Thoracic & Cardiac Surgery - New York, NY". Castle Connolly. Retrieved 2022-06-17.
  13. "Dr. John Puskas, MD, Cardiothoracic Surgery Specialist - New York, NY". Sharecare. Retrieved 2022-06-17.
  14. "John Puskas | CTSNet". www.ctsnet.org. Retrieved 2022-08-25.
  15. "NIH RePorter". NIH Reporter.
  16. "NIH RePorter". NIH. Retrieved 17 June 2022.
  17. Puskas, John D.; Williams, Willis H.; Mahoney, Elizabeth M.; Huber, Philip R.; Block, Peter C.; Duke, Peggy G.; Staples, James R.; Glas, Katherine E.; Marshall, J. Jeffrey; Leimbach, Mark E.; McCall, Susan A. (2004-04-21). "Off-Pump vs Conventional Coronary Artery Bypass Grafting: Early and 1-Year Graft Patency, Cost, and Quality-of-Life OutcomesA Randomized Trial". JAMA. 291 (15): 1841–1849. doi:10.1001/jama.291.15.1841. ISSN 0098-7484. PMID 15100202.
  18. "Emory Surgery Newsletter | February 28, 2014". www.surgery.emory.edu. Retrieved 2022-08-25.
  19. "TECAB reduces risk, expedites recovery for bypass patients". cardiovascularbusiness.com. Retrieved 2022-08-25.
  20. "Puskas JD - Search Results - PubMed". PubMed. Retrieved 2022-06-17.
  21. Smith, Peter K.; Puskas, John D.; Ascheim, Deborah D.; Voisine, Pierre; Gelijns, Annetine C.; Moskowitz, Alan J.; Hung, Judy W.; Parides, Michael K.; Ailawadi, Gorav; Perrault, Louis P.; Acker, Michael A. (2014-12-04). "Surgical Treatment of Moderate Ischemic Mitral Regurgitation". New England Journal of Medicine. 371 (23): 2178–2188. doi:10.1056/NEJMoa1410490. ISSN 0028-4793. PMC 4303577. PMID 25405390.
  22. Puskas, John D; Thourani, Vinod H; Marshall, J. Jeffrey; Dempsey, Steven J; Steiner, Mark A; Sammons, Bonnie H; Brown, W. Morris; Gott, John Parker; Weintraub, William S; Guyton, Robert A (2001-05-01). "Clinical outcomes, angiographic patency, and resource utilization in 200 consecutive off-pump coronary bypass patients". The Annals of Thoracic Surgery. 71 (5): 1477–1484. doi:10.1016/S0003-4975(01)02473-0. ISSN 0003-4975. PMID 11383786.
  23. Gaudino, Mario; Benedetto, Umberto; Fremes, Stephen; Biondi-Zoccai, Giuseppe; Sedrakyan, Art; Puskas, John D.; Angelini, Gianni D.; Buxton, Brian; Frati, Giacomo; Hare, David L.; Hayward, Philip (2018-05-31). "Radial-Artery or Saphenous-Vein Grafts in Coronary-Artery Bypass Surgery". New England Journal of Medicine. 378 (22): 2069–2077. doi:10.1056/NEJMoa1716026. ISSN 0028-4793. PMID 29708851. S2CID 13752332.
  24. Gillinov, A. Marc; Gelijns, Annetine C.; Parides, Michael K.; DeRose, Joseph J.; Moskowitz, Alan J.; Voisine, Pierre; Ailawadi, Gorav; Bouchard, Denis; Smith, Peter K.; Mack, Michael J.; Acker, Michael A. (2015-04-09). "Surgical Ablation of Atrial Fibrillation during Mitral-Valve Surgery". New England Journal of Medicine. 372 (15): 1399–1409. doi:10.1056/NEJMoa1500528. ISSN 0028-4793. PMC 4664179. PMID 25853744.
  25. El, -Chami Mikhael F.; Kilgo, Patrick; Thourani, Vinod; Lattouf, Omar M.; Delurgio, David B.; Guyton, Robert A.; Leon, Angel R.; Puskas, John D. (2010-03-30). "New-Onset Atrial Fibrillation Predicts Long-Term Mortality After Coronary Artery Bypass Graft". Journal of the American College of Cardiology. 55 (13): 1370–1376. doi:10.1016/j.jacc.2009.10.058. PMID 20338499.
  26. Puskas, John D. "Tips and Techniques for Multivessel OPCAB". Operative Techniques. Retrieved August 24, 2022.
  27. Keeling, W. Brent; Thourani, Vinod H. (2013), Lubin, Michael F.; Winawer, Neil H.; Dodson, Thomas F. (eds.), "Coronary artery bypass procedures", Medical Management of the Surgical Patient: A Textbook of Perioperative Medicine (5 ed.), Cambridge: Cambridge University Press, pp. 557–564, ISBN 978-1-107-00916-5, retrieved 2022-08-25
  28. Puskas, John D.; Thourani, Vinod H.; Kilgo, Patrick; Cooper, William; Vassiliades, Thomas; Vega, J. David; Morris, Cullen; Chen, Edward; Schmotzer, Brian J.; Guyton, Robert A.; Lattouf, Omar M. (2009). "Off-pump coronary artery bypass disproportionately benefits high-risk patients". The Annals of Thoracic Surgery. 88 (4): 1142–1147. doi:10.1016/j.athoracsur.2009.04.135. ISSN 1552-6259. PMID 19766798.
  29. Puskas, John D.; Williams, Willis H.; O'Donnell, Robert; Patterson, Randolph E.; Sigman, Steven R.; Smith, A. Shannon; Baio, Kim T.; Kilgo, Patrick D.; Guyton, Robert A. (2011). "Off-pump and on-pump coronary artery bypass grafting are associated with similar graft patency, myocardial ischemia, and freedom from reintervention: long-term follow-up of a randomized trial". The Annals of Thoracic Surgery. 91 (6): 1836–1842, discussion 1842–1843. doi:10.1016/j.athoracsur.2010.12.043. ISSN 1552-6259. PMID 21619980.
  30. Moorjani, Narain; Ohri, Sunil K.; Wechsler, Andrew (2013-12-17). Cardiac Surgery: Recent Advances and Techniques. CRC Press. ISBN 978-1-4441-3756-9.
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