Jpx (gene)

In molecular biology, JPX transcript, XIST activator (non-protein coding), also known as Jpx, is a long non-coding RNA. In humans, it is located on the X chromosome. It was identified during sequence analysis of the X inactivation centre, surrounding the Xist gene.[3] Jpx upregulates expression of Xist.[4]

JPX
Identifiers
AliasesJPX, DCBALD06, ENOX, LINC00183, NCRNA00183, Jpx, JPX transcript, XIST activator (non-protein coding), JPX transcript, XIST activator
External IDsOMIM: 300832 GeneCards: JPX
Orthologs
SpeciesHumanMouse
Entrez

554203

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Ensembl

ENSG00000225470

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)Chr X: 73.94 – 74.07 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

See also

References

  1. GRCh38: Ensembl release 89: ENSG00000225470 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. Chureau C, Prissette M, Bourdet A, Barbe V, Cattolico L, Jones L, et al. (2002). "Comparative sequence analysis of the X-inactivation center region in mouse, human, and bovine". Genome Res. 12 (6): 894–908. doi:10.1101/gr.152902. PMC 1383731. PMID 12045143.
  4. Tian D, Sun S, Lee JT (2010). "The long noncoding RNA, Jpx, is a molecular switch for X chromosome inactivation". Cell. 143 (3): 390–403. doi:10.1016/j.cell.2010.09.049. PMC 2994261. PMID 21029862.

Further reading

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