Judith Klein-Seetharaman
Judith Klein-Seetharaman (born May 30, 1971) is an American-German biochemist who is a professor at the Arizona State University. Her research considers the structure-function properties of proteins using computational bio-linguistics. She was supported by the Bill & Melinda Gates Foundation to identify novel therapies to tackle HIV.
Judith Klein-Seetharaman | |
|---|---|
| Born | May 30, 1972 |
| Alma mater | University of Cologne Massachusetts Institute of Technology |
| Scientific career | |
| Institutions | Carnegie Mellon Colorado School of Mines Arizona State University University of Warwick University of Pittsburgh |
| Thesis | Visual signal transduction : studies of light-induced conformational changes in the cytoplasmic face of rhodopsin. (2000) |
Early life and education
Klein-Seetharaman was born in Germany. She completed her undergraduate training at the University of Cologne, where she earned dual honours in biology and chemistry.[1][2] After earning her doctorate, she moved to the United States, where she worked in the laboratory of Har Gobind Khorana at the Massachusetts Institute of Technology.[1][2] Her research considered conformational changes in rhodopsin, the G protein coupled receptor.[3] She was a postdoctoral researcher at MIT with Harald Schwalbe, focusing on nuclear magnetic resonance spectroscopy. After eight months as a postdoc, Klein-Seetharaman moved Carnegie Mellon University where she worked with Raj Reddy in biology. She was eventually appointed to the faculty at Carnegie Mellon.[1][4]
Research and career
Klein-Seetharaman moved to the University of Pittsburgh as an assistant professor in 2002 and was promoted to associate professor in 2009.[1] She joined the Warwick Medical School as a professor in medicine in 2013.[1] She returned to the[United States in 2017, first as a professor at the Colorado School of Mines and then as a professor at the Arizona State University in 2021.[1] Her research looks to uncover the structure-property relationships of membrane proteins.[2]
Selected publications
- Valerian E Kagan; Gaowei Mao; Feng Qu; et al. (14 November 2016). "Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis". Nature Chemical Biology. 13 (1): 81–90. doi:10.1038/NCHEMBIO.2238. ISSN 1552-4450. PMC 5506843. PMID 27842066. Wikidata Q33897013.
- Charleen T. Chu; Jing Ji; Ruben K. Dagda; et al. (October 2013). "Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells". Nature Cell Biology. 15 (10): 1197–205. doi:10.1038/NCB2837. ISSN 1465-7392. PMC 3806088. PMID 24036476. Wikidata Q23910949.
- Valerian E. Kagan; Nagarjun V. Konduru; Weihong Feng; et al. (4 April 2010). "Carbon nanotubes degraded by neutrophil myeloperoxidase induce less pulmonary inflammation". Nature Nanotechnology. 5 (5): 354–359. Bibcode:2010NatNa...5..354K. doi:10.1038/NNANO.2010.44. ISSN 1748-3387. OCLC 612999337. PMC 6714564. PMID 20364135. S2CID 13364775. Wikidata Q23923187.
References
- Judith Klein-Seetharaman. OCLC 4779998271.
- "Judith Klein-Seetharaman | iSearch". isearch.asu.edu. Retrieved 2022-03-27.
- Klein, Judith (2000). Visual signal transduction: studies of light-induced conformational changes in the cytoplasmic face of rhodopsin (Thesis). OCLC 48061756.
- "Bill & Melinda Gates Foundation Awards Grant to Judith Klein-Seetharaman, a research scientist in Carnegie Mellon University's Language Technologies Institute for Innovative HIV Research". www.cs.cmu.edu. Retrieved 2022-03-28.