Julie Segre

Julie Angela Segre is the Chief and Senior Investigator of the Translational and Functional Genomics Branch in the National Human Genome Research Institute at the National Institutes of Health.[4] She was elected to the National Academy of Medicine in 2019,[5] the American Academy of Arts and Sciences in 2020[6] and the National Academy of Sciences in 2022.[7]

Julie A. Segre
Photo of Julie Segre
Julie A. Segre, Ph.D. Senior Investigator, National Human Genome Research Institute (NHGRI), National Institutes of Health (NIH).
Born
Berkeley, California, U.S.
Alma mater
Known for
  • Foundational studies of the human skin associated microbes (bacteria, fungi, viruses)skin flora[1]
  • Using DNA sequencing to track antibiotic-resistant bacteria in hospitals.

[2]

  • NIH 'superbug' was thwarted with help of two scientists

[3]

Scientific career
Fields
  • Microbial Genomics
  • Genetics and Molecular Biology
Institutions
Academic advisorsEric Lander, Elaine Fuchs

Early life and education

Segre was born in Berkeley, California, the daughter of Nina and Gino Claudio Segrè. She was raised in Philadelphia, where her father was a professor of physics at the University of Pennsylvania. Segre received her B.A. summa cum laude in mathematics from Amherst College in 1987,[8] where she later served on the board of trustees.[9] She received her Ph.D. in 1996 from the Massachusetts Institute of Technology. Segre then performed postdoctoral training in Molecular Genetics and Cell Biology at the University of Chicago (1996-2000).

Research and career

Segre came to the National Human Genome Research Institute of NIH in 2000 and was promoted to a senior investigator with tenure in 2007.[10]

Segre's laboratory studies how the epidermis interfaces between the body and the environment.[11] Using genomic methodologies, Segre studies the bacteria and microbes of the skin microbiome.[11] Segre's laboratory also develops genomic tools to track hospital-acquired infections of multi-drug resistant organisms. [12] [13]


Medical and research achievements

References
  1. Byrd, A. L.; Belkaid, Y.; Segre, J. A. (2018). "The human skin microbiome". Nature Reviews. Microbiology. 16 (3): 143–155. doi:10.1038/nrmicro.2017.157. PMID 29332945. S2CID 46781506.
  2. Zimmer, Carl. "How Scientists Stalked a Lethal Superbug—With the Killer's Own DNA". Wired.
  3. "NIH 'superbug' was thwarted with help of two scientists". The Washington Post.
  4. "Julie Segre biography".
  5. "National Academy of Medicine". 21 October 2019.
  6. "New Members". American Academy of Arts & Sciences. Retrieved 2020-04-23.
  7. "National Academy of Sciences". 3 May 2022.
  8. Women in Science at National Institutes of Health 2007-2008. U.S. Department of Health and Human Services. pp. 63–64.
  9. "Amherst Trustees".
  10. "NHGRI genome.gov".
  11. "NIH Intramural Research Program".
  12. Johnson, Ryan C.; Deming, Clay; Conlan, Sean; Zellmer, Caroline J.; Michelin, Angela V.; Lee-Lin, Shihqueen; Thomas, Pamela J.; Park, Morgan; Weingarten, Rebecca A.; Less, John; Dekker, John P.; Frank, Karen M.; Musser, Kimberlee A.; McQuiston, John R.; Henderson, David K.; Lau, Anna F.; Palmore, Tara N.; Segre, Julia A. (2018). "Investigation of a Cluster of Sphingomonas koreensis Infections". New England Journal of Medicine. 379 (26): 2529–2539. doi:10.1056/NEJMoa1803238. PMC 6322212. PMID 30586509.
  13. Conlan, Sean; Thomas, Pamela J.; Deming, Clayton; Park, Morgan; Lau, Anna F.; Dekker, John P.; Snitkin, Evan S.; Clark, Tyson A.; Luong, Khai; Song, Yi; Tsai, Yu-Chih; Boitano, Matthew; Dayal, Jyoti; Brooks, Shelise Y.; Schmidt, Brian; Young, Alice C.; Thomas, James W.; Bouffard, Gerard G.; Blakesley, Robert W.; Mullikin, James C.; Korlach, Jonas; Henderson, David K.; Frank, Karen M.; Palmore, Tara N.; Segre, Julia A.; Segre, J. A. (2014). "Single-molecule sequencing to track plasmid diversity of hospital-associated carbapenemase-producing Enterobacteriaceae". Science Translational Medicine. 6 (254): 254ra126. doi:10.1126/scitranslmed.3009845. PMC 4203314. PMID 25232178.
  14. Samuel J. Heyman Service to America Medals. "2013 Federal Employees of the Year". Partnership for Public Service. Archived from the original on 2 April 2015. Retrieved 15 March 2015.
  15. "Federal 'Employee of the Year' Honorees Hail from NIH".
  16. "79 Fellows elected to the American Academy of Microbiology".
  17. "National Academy of Medicine". 21 October 2019.
  18. "New Members". American Academy of Arts & Sciences. Retrieved 2020-04-23.
  19. "National Academy of Sciences". 3 May 2022.
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