KC
Places
- Kuçovë District, Albania's ISO 3166-2 code
- Kansas City metropolitan area, a major metropolitan area of the United States
- Kansas City, Missouri, its principal city
- Kansas City, Kansas, the third-largest city in the region
- Karachay-Cherkessia, Russia's ISO 3166-2 code
People
- Kent Cochrane (1951–2014), Canadian memory disorder patient
- KC Concepcion (born 1985), Philippine model, actress, singer, songwriter
- Kcee (musician) (born 1979), Nigerian singer, songwriter, performer
- K.C. Potter (born 1939), American academic administrator and LGBT rights activist
- Harry Wayne Casey (born 1951), American musician best known for his band KC and the Sunshine Band
- Govinda K.C. (born 1957), Nepali orthopaedic surgeon and philanthropic activist
- KC or K.C., an abbreviation for the Nepalese surname Khatri (Khatri Chhetri)
Arts and entertainment
- KC (album), a 2010 album by KC Concepcion
- KC and the Sunshine Band, an American funk, R&B and disco musical group founded in 1973
- King Crimson, a British progressive rock band
- K.C. Guthrie, a fictional character in Degrassi: The Next Generation
Businesses and organizations
Schools and universities
- King's College, Hong Kong, a boys' secondary school in Hong Kong
- Kingwood College, now Lone Star College-Kingwood, in Kingwood, Houston, Texas, United States
- Kishinchand Chellaram College or K. C. College, South Mumbai, India
- Kutama College, a boys' boarding high school in Zimbabwe
- Kuen Cheng High School, a high school in Malaysia
Sports organizations
- Kansas City Chiefs, a National Football League team based in Kansas City, Missouri
- Kansas City Royals, a Major League Baseball team based in Kansas City, Missouri
- Sporting Kansas City or Sporting KC, a Major League Soccer team based in Kansas City, Kansas
Other businesses and organizations
- KC HiLiTES, a US manufacturer of driving lights
- Kimberly-Clark, a US personal care corporation
- The Kennel Club, a dog-breed registry in England
- Kingston Communications, a UK communications and IT service provider
- Air Astana (IATA airline designator)
Science and technology
- Kc, the equilibrium constant, the equilibrium of a chemical reaction
- CXCL1 or KC, a cytokine
- Keratoconus, a degenerative eye disease
- Kilocycle, as in 1,000 cycles per second, with the modern equivalent being kilohertz
Other uses
- KC Stadium, a former name of a football and rugby-league stadium in Hull, England
- Kelly criterion, a formula in probability theory and finance
- King's Counsel, a legal position in Commonwealth countries
- KC, an obsolete postnominal for Knight of the Order of the Crescent
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