KDM1B

Lysine (K)-specific demethylase 1B is a protein that in humans is encoded by the KDM1B gene.[3]

KDM1B
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
AliasesKDM1B, AOF1, C6orf193, LSD2, bA204B7.3, dJ298J15.2, lysine demethylase 1B
External IDsOMIM: 613081 HomoloGene: 131158 GeneCards: KDM1B
Orthologs
SpeciesHumanMouse
Entrez

221656

n/a

Ensembl

ENSG00000165097

n/a

UniProt

Q8NB78

n/a

RefSeq (mRNA)

NM_153042
NM_001364614

n/a

RefSeq (protein)

NP_694587
NP_001351543

n/a

Location (UCSC)Chr 6: 18.16 – 18.22 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Function

Flavin-dependent histone demethylases, such as KDM1B, regulate histone lysine methylation, an epigenetic mark that regulates gene expression and chromatin function.[3][4]

References

  1. GRCh38: Ensembl release 89: ENSG00000165097 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. "Entrez Gene: Lysine (K)-specific demethylase 1B".
  4. Karytinos A, Forneris F, Profumo A, Ciossani G, Battaglioli E, Binda C, Mattevi A (Jun 2009). "A novel mammalian flavin-dependent histone demethylase". The Journal of Biological Chemistry. 284 (26): 17775–82. doi:10.1074/jbc.M109.003087. PMC 2719416. PMID 19407342.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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