Yoshito Kishi

Yoshito Kishi (岸 義人, Kishi Yoshito, 13 April 1937 – 9 January 2023)[1] was a Japanese chemist who was the Morris Loeb Professor of Chemistry at Harvard University. He was known for his contributions to the sciences of organic synthesis and total synthesis.

Yoshito Kishi
Kishi in 2003
Born(1937-04-13)13 April 1937
Nagoya, Japan
Died9 January 2023(2023-01-09) (aged 85)
Alma materNagoya University (BS, PhD)
Scientific career
FieldsOrganic chemistry
InstitutionsNagoya University
Harvard University
Thesisウミホタルルシフェリンの構造とその全合成 (1966)
Doctoral advisorYoshimasa Hirata
Doctoral studentsTohru Fukuyama
Stuart L. Schreiber
Other notable studentsRené Peters (chemist)

Early life and education

Kishi was born in Nagoya, Japan and attended Nagoya University, where he obtained both his BS and PhD degrees.[2][3] He was a postdoctoral research fellow at Harvard University where he worked with Robert Burns Woodward.[3] From 1966 through 1974, he was a professor of chemistry at Nagoya University.[3] Since 1974, Kishi had been a professor of chemistry at Harvard University.[4][5]

Kishi's research has focused on the total synthesis of complex natural products. The accomplishments of his research group include the total syntheses of palytoxin, mycolactones, halichondrins, saxitoxin, tetrodotoxin, geldanamycin, batrachotoxin and many others.[6][7][8] Kishi has also contributed to the development of new chemical reactions including the Nozaki–Hiyama–Kishi reaction.[9]

Recognition

See also

References
  1. 岸義人氏が死去　天然物有機化学者 (in Japanese)
  2. Williams, Robert M. (2007). "Preface: Honoring the 70th Birthday of Professor Yoshito Kishi". Heterocycles. 72 (1): 1–3. doi:10.3987/2007-72-0001. Retrieved 26 February 2023.
  3. Kishi, Yoshito; Rando, Robert R. (1998). "Structural Basis of Protein Kinase C Activation by Tumor Promoters". Accounts of Chemical Research. 31 (4): 9672–6. doi:10.1021/ar9600751. PMC 298563. PMID 2602368.
  4. Chaudhry, Yahya (31 January 2023). "Yoshito Kishi, 86, remembered for developing important anti-cancer agent". Harvard Gazette. Retrieved 26 February 2023.
  5. Wang, Austin H. (21 March 2023). "Yoshito Kishi, Organic Chemist Who Climbed 'Mount Everest' of Synthesis, Dies at 85". Harvard Crimson. Retrieved 25 March 2023.
  6. Yoshito Kishi Archived October 18, 2010, at the Wayback Machine, Department of Chemistry and Chemical Biology, Harvard University
  7. Lowe, Derek (January 18, 2023). "Prof. Yoshito Kishi, 1937-2023". Science. Retrieved 26 February 2023.
  8. Krietsch Boerner, Leigh (January 24, 2023). "Organic chemist Yoshito Kishi dies at 85". cen.acs.org. 101 (4). Retrieved 26 February 2023.
  9. Takai, K.; Tagashira, M.; Kuroda, T.; Oshima, K.; Utimoto, K.; Nozaki, H. (1986). "Reactions of alkenylchromium reagents prepared from alkenyl trifluoromethanesulfonates (triflates) with chromium(II) chloride under nickel catalysis". Journal of the American Chemical Society. 108 (19): 6048–50. doi:10.1021/ja00279a068. PMID 22175376.
  10. "Tetrahedron Prize for Creativity in Organic Chemistry or Bioorganic & Medicinal Chemistry". Elsevier. Archived from the original on September 9, 2014. Retrieved 28 January 2015.


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