LARS2

Probable leucyl-tRNA synthetase, mitochondrial is an enzyme that in humans is encoded by the LARS2 gene.[5][6]

LARS2
Identifiers
AliasesLARS2, LEURS, PRLTS4, mtLeuRS, leucyl-tRNA synthetase 2, mitochondrial, HLASA
External IDsOMIM: 604544 MGI: 2142973 HomoloGene: 6526 GeneCards: LARS2
Orthologs
SpeciesHumanMouse
Entrez

23395

102436

Ensembl

ENSG00000011376

ENSMUSG00000035202

UniProt

Q15031

Q8VDC0

RefSeq (mRNA)

NM_015340
NM_001368263

NM_153168
NM_001348167
NM_001348168

RefSeq (protein)

NP_056155
NP_001355192

NP_694808
NP_001335096
NP_001335097

Location (UCSC)Chr 3: 45.39 – 45.55 MbChr 9: 123.2 – 123.29 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes a class 1 aminoacyl-tRNA synthetase, mitochondrial leucyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid.[6]

References

  1. GRCh38: Ensembl release 89: ENSG00000011376 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000035202 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Sohm B, Sissler M, Park H, King MP, Florentz C (May 2004). "Recognition of human mitochondrial tRNALeu(UUR) by its cognate leucyl-tRNA synthetase". J Mol Biol. 339 (1): 17–29. doi:10.1016/j.jmb.2004.03.066. PMID 15123417.
  6. "Entrez Gene: LARS2 leucyl-tRNA synthetase 2, mitochondrial".

Further reading


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.