LYPD1

Ly6/PLAUR domain-containing protein 1 is a protein that in humans is encoded by the LYPD1 gene.[5][6]

LYPD1
Identifiers
AliasesLYPD1, LYPDC1, PHTS, LY6/PLAUR domain containing 1
External IDsOMIM: 610450 MGI: 1919835 HomoloGene: 16937 GeneCards: LYPD1
Orthologs
SpeciesHumanMouse
Entrez

116372

72585

Ensembl

ENSG00000150551

ENSMUSG00000026344

UniProt

Q8N2G4

Q8BLC3

RefSeq (mRNA)

NM_001077427
NM_144586
NM_001321234
NM_001321235

NM_145100
NM_001311089
NM_001311090

RefSeq (protein)

NP_001070895
NP_001308163
NP_001308164
NP_653187

NP_001298018
NP_001298019
NP_659568

Location (UCSC)Chr 2: 132.64 – 132.67 MbChr 1: 125.8 – 125.84 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This protein is also known as Lynx2, a member of the Lynx family of neurotransmitter receptor-binding proteins.[7] Transgenic mice without Lynx2 expression have increased anxiety-related behaviors.[8]


References

  1. GRCh38: Ensembl release 89: ENSG00000150551 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000026344 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  6. "Entrez Gene: LYPD1 LY6/PLAUR domain containing 1".
  7. Miwa, J. M.; Lester, H. A.; Walz, A. (2012). "Optimizing Cholinergic Tone Through Lynx Modulators of Nicotinic Receptors: Implications for Plasticity and Nicotine Addiction". Physiology. 27 (4): 187–199. doi:10.1152/physiol.00002.2012. PMID 22875450.
  8. Tekinay, A. B.; Nong, Y.; Miwa, J. M.; Lieberam, I.; Ibanez-Tallon, I.; Greengard, P.; Heintz, N. (2009). "A role for LYNX2 in anxiety-related behavior". Proceedings of the National Academy of Sciences. 106 (11): 4477–4482. Bibcode:2009PNAS..106.4477T. doi:10.1073/pnas.0813109106. PMC 2657456. PMID 19246390.

Further reading


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