Lactate permease family

The lactate permease (LctP) family (TC# 2.A.14) is a family of transport proteins belonging to the ion transporter (IT) superfamily.[1]

Lactate permease
Identifiers
SymbolLctP
PfamPF02652
InterProIPR003804
TCDB2.A.14
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary

Function

Characterized members of this family possess 15-18 transmembrane segments (TMSs) and are roughly 460-565 amino acyl residues in length.

General transport reaction

Transport reactions catalyzed by functionally characterized members of the LctP family include:[2]

D- or L-lactate or glycolate (out) + H+ (out) → D- or L-lactate or glycolate (in) + H+ (in).

References

  1. Prakash S, Cooper G, Singhi S, Saier MH (December 2003). "The ion transporter superfamily". Biochimica et Biophysica Acta (BBA) - Biomembranes. 1618 (1): 79–92. doi:10.1016/j.bbamem.2003.10.010. PMID 14643936.
  2. "2.A.14 The Lactate Permease (LctP) Family". Transporter Classification Database. Retrieved 2016-03-02.

Further reading

As of 12 March 2016, this article is derived in whole or in part from Transporter Classification Database. The copyright holder has licensed the content in a manner that permits reuse under CC BY-SA 3.0 and GFDL. All relevant terms must be followed. The original text was at "2.A.14 The Lactate Permease (LctP) Family"

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